Research Assistant | Laboratory of Chemical Immunology and Proteomics
About The Position
The Research Assistant will support ongoing research projects investigating the molecular mechanisms that regulate immune cell function, with a focus on T helper cell biology and neuroinflammation. The work involves experiments using primary immune cells, molecular and cellular biology techniques, and support for studies using mouse models of neuroinflammation. The Laboratory of Chemical Immunology and Proteomics applies synthetic chemistry, chemical biology, and proteomics methods to discover and characterize selective chemical probes, mechanisms of small-molecule-induced protein degradation, and pharmacological landscapes and signal transduction pathways in immune and neuroimmunological disorders. The laboratory develops and applies chemical proteomic profiling technologies to study molecular differences between pathological and physiological states in immune and nervous-system cells and to support development of therapies targeting specific immune cell subtypes and activation states.
Requirements
- Bachelor's degree in biology, biochemistry, immunology, molecular biology, or a related scientific discipline.
- At least 2 years of extensive laboratory research experience through undergraduate coursework, internships, or independent research projects.
- Familiarity with basic molecular and cellular biology techniques.
- Strong organizational skills and attention to detail, with the ability to maintain accurate experimental records.
- Excellent communication skills and the ability to work independently and collaboratively in a research environment.
- Willingness to work with laboratory mice and complete required institutional training.
Nice To Haves
- Experience with flow cytometry.
- Experience with PCR/RT-PCR.
- Experience with SDS-PAGE.
- Experience with Western blotting.
- Experience with cloning.
- Experience with viral transduction.
- Experience with CRISPR-Cas9 gene editing.
- Experience with protein expression.
- Experience with biochemical assay development.
- Experience working with murine models.
Responsibilities
- Conduct experiments investigating T helper cell activation, differentiation, and function.
- Perform molecular and cellular assays, including flow cytometry, immunoblotting, and other biochemical techniques, to characterize immune cell responses.
- Assist a postdoctoral researcher with animal studies investigating neuroinflammation.
- Analyze experimental data, maintain accurate laboratory records, and participate in laboratory meetings and discussions of research findings.
- Prepare reagents, maintain laboratory supplies and equipment, and support routine laboratory operations.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
