Research Assistant

Labcorp•Madison, WI

8d•Onsite

About The Position

Labcorp is seeking an Research Assistant to join our Metabolism team in Madison, WI. This role involves organizing and performing method validation activities, executing advanced validation tasks, and interpreting data using analytical instrumentation. The Research Assistant will also review reports, manage project work, collaborate with colleagues and clients, and train junior staff. The position contributes to process improvement and quality initiatives, and requires maintaining a safe laboratory environment.

Requirements

Bachelor's degree in Life Sciences, Chemistry, Biotechnology, or a related field.
6 months or more hands-on experience with LC-MS/MS bioanalysis, including MRM-based quantitation and method execution.
1 or more years of experience with ADME/PK assays such as liver microsomal stability, permeability assays (e.g., MDCK-MDR1), and PK sample processing (plasma, tissue lysates).
Proficiency with data acquisition and processing software (Mass Lynx, Mass Hunter, Analyst, or equivalent).
Proficiency with ELN documentation, word processing, spreadsheet, and specialized analytical software.
Strong attention to detail with demonstrated ability to generate reproducible, high-quality bioanalytical data.
Excellent written and verbal communication skills.
Proven ability to prioritize workloads and manage time effectively in a fast-paced laboratory environment.

Nice To Haves

1 or more years of exposure to CYP inhibition or Time-Dependent Inhibition (TDI) assays and drug-drug interaction (DDI) studies.
1 or more years of experience assisting in the development or optimization of new bioanalytical methods.
Master's degree or other post graduate studies in a relevant life sciences discipline.
Familiarity with Orbitrap platforms or other high-resolution mass spectrometry systems.
Knowledge of regulatory guidelines including FDA, EMA, and ICH bioanalytical method validation guidance.
Experience working in a GLP/GCP-regulated environment (CRO or pharmaceutical/biotech industry).

Responsibilities

Organize and independently perform routine to moderate-level method validation activities in compliance with SOPs and regulatory guidelines (GLP/GCP).
Execute advanced method validation tasks with guidance from a Lead Scientist.
Apply intermediate data interpretation and analytical instrumentation skills to resolve procedural and scientific problems with minimal assistance.
Assist in the review of reports, methods, protocols, and SOPs; maintain complete and audit-ready study documentation.
Communicate problems, deviations, and corrective actions to Lead Scientist and/or management in a timely manner.
Manage assigned project work, coordinating activities with team members to deliver high-quality data to internal clients on schedule.
Collaborate effectively with colleagues across the Bioanalytical site and support cross-functional communications with external clients.
Train and mentor less experienced laboratory staff.
Contribute to process improvement initiatives and participate in department-wide quality initiatives.
Maintain a clean, safe, and organized laboratory environment.