Regional Medical Director, Value and Access - West

Stoke Therapeutics•Bedford, MA

14d•$240,000 - $280,000•Remote

About The Position

The Regional Medical Director, Value and Access is a senior, field-based Medical Affairs leader responsible for developing and executing regional medical value strategy. The role serves as a scientific and strategic partner to payers, pharmacy benefit managers, integrated delivery networks, accountable care organizations, Medicaid stakeholders, health technology assessment bodies, and other population-health decision-makers. It leads unbiased scientific exchange and translates clinical, health-economic, and real-world evidence into decision-relevant value narratives to inform formulary evaluation, coverage, reimbursement readiness, and patient access. Working with substantial autonomy, the role partners with Field Medical, Market Access, HEOR/RWE, Clinical Development, Regulatory, and Policy. It is particularly important during pre-launch, launch, and lifecycle management, building scientific credibility with priority payers and anticipating evidence needs. This is a remote position; the employee must reside within or have practical access to the assigned region and be able to travel overnight as business needs require. Approximately 50–70% domestic travel is expected. Stoke Therapeutics is a biotechnology company developing RNA medicines using its proprietary TANGO approach to restore naturally occurring protein levels. The company is headquartered in Bedford, Massachusetts, and plans to move to Waltham, Massachusetts, by the end of 2026. The anticipated salary range is $240,000–$280,000, with the final offer dependent on factors including scope, qualifications, experience, market benchmarks, internal equity, and location. The total rewards package also includes an annual bonus and equity participation.

Requirements

Advanced clinical or scientific degree in a relevant discipline.
10+ years of progressive experience in Medical Affairs, payer medical engagement, Market Access, HEOR/RWE, clinical development, managed care, or a related pharmaceutical or biotechnology function.
Deep expertise in managed care, formulary and coverage decision-making, evidence-based medicine, clinical trial methodology, HEOR, outcomes research, epidemiology, and real-world evidence.
Ability to connect external stakeholder needs with portfolio, evidence-generation, access, and medical priorities.
Executive-level scientific communication, facilitation, and presentation skills.
Ability to critically appraise complex clinical and economic data, identify limitations, and articulate implications for population-health decisions.
Strong business and financial acumen, including prioritization, resource allocation, project planning, and impact measurement.
Proven ability to influence in matrixed organizations and lead across functions, geographies, and levels without direct authority.
Sound judgment in ambiguous, high-visibility, and compliance-sensitive situations.
Strong coaching, mentoring, change leadership, and capability-building skills.
Ability to use digital engagement, insight analytics, and customer relationship tools effectively.
Must reside within or have practical access to the assigned region and be able to travel overnight as business needs require.
Ability to support approximately 50–70% domestic travel.

Nice To Haves

Formal training or demonstrated expertise in health economics, outcomes research, population health, managed care, epidemiology, or health policy is strongly preferred.

Responsibilities

Develop and execute a regional stakeholder engagement plan aligned with medical, evidence, and corporate priorities.
Build peer-to-peer scientific relationships with senior clinical and population-health leaders across health plans, PBMs, Medicaid organizations, IDNs, ACOs, employer coalitions, and HTA bodies.
Serve as the senior scientific contact for complex payer and reimbursement questions, including pre-launch and launch engagements.
Lead balanced, non-promotional scientific exchange on disease state, clinical data, guidelines, safety and efficacy, comparative evidence, HEOR, RWE, and appropriate pipeline information.
Plan and conduct payer advisory boards and scientific forums, ensuring insights are captured and acted upon.
Represent Medical Affairs at regional and national payer meetings and external forums.
Lead regional communication of the totality of evidence, including efficacy, safety, comparative data, HEOR, quality of life, budget impact, epidemiology, and RWE.
Develop and maintain payer-facing scientific materials and evidence summaries through appropriate review processes.
Translate complex evidence into clear, decision-relevant scientific narratives and keep resources current, rigorous, and aligned with stakeholder needs.
Own the regional medical value plan and contribute to annual and lifecycle planning, prioritization, and resource allocation.
Gather and synthesize actionable insights on unmet needs, evidence expectations, coverage and policy changes, treatment paradigms, and competitive dynamics.
Escalate regional trends and strategic implications to Medical Affairs leadership and cross-functional governance.
Translate insights into recommendations for medical strategy, evidence generation, clinical development, publications, market access, and education.
Define and monitor regional Medical objectives, KPIs, and impact, adjusting plans as needed.
Provide senior scientific judgment for portfolio, indication, and lifecycle decisions while preserving Medical Affairs independence.
Provide regional leadership and strategic counsel across Medical Affairs, Field Market Access, HEOR/RWE, Clinical Development, Commercial within compliance guidelines, Government Affairs, Patient Services, Regulatory, Policy, and Medical Information.
Lead cross-functional workstreams for launch planning, payer evidence planning, advisory boards, congress strategy, and medical education.
Influence priorities and resolve competing needs without direct authority.
Coach and mentor colleagues; Senior Director incumbents may also lead teams, vendors, budgets, or enterprise initiatives.
Inform regional resource allocation, manage assigned project budgets and external partners, and represent the regional perspective in US and global planning forums.
Identify and prioritize payer-relevant evidence gaps.
Partner with HEOR/RWE, Epidemiology, Clinical Development, and Market Access on evidence plans, research questions, endpoints, and dissemination.
Initiate or lead payer research collaborations, pragmatic pilots, data partnerships, investigator-sponsored research, and RWE projects.
Provide senior field input into protocol concepts, publication strategy, congress communications, and medical information resources.
Evaluate emerging evidence and recommend changes to regional strategy and engagement.
Comply with applicable laws, industry codes, company policies, and SOPs; maintain separation between scientific exchange and promotion.
Document and manage insights, engagements, research collaborations, materials, and transfers of value appropriately.
Identify operational risks, drive continuous improvement, and contribute to scalable field medical value processes.
Complete required training and reporting accurately and on time.