(Senior) RA, Chemistry

Nosis Bio • Alameda, CA

2d • Onsite

About The Position

Nosis Bio is seeking a Research Associate or Senior Research Associate to conduct chemical synthesis, chromatographic purification, and biochemical validation of peptides, oligonucleotides, and oligo-peptide conjugates in support of therapeutic candidate development. The successful candidate will have hands-on peptide chemistry experience and will work with multidisciplinary teams on drug discovery projects. The title depends on academic and professional experience; candidates from academic, nonprofit, and industry backgrounds are welcome.

The role is based in Nosis Bio’s laboratory spaces at Research Park at Marina Village in Alameda, California, and requires on-site work.

Requirements

• Experience with solid-phase peptide synthesis and downstream processing, including cleavage, deprotection, and purification.
• Experience performing in vitro biochemical assays.
• Ability to work on site in the company’s laboratory spaces in Alameda, California.
• Motivation, proactivity, and strong problem-solving skills.
• Ability to multitask and manage several projects simultaneously.
• Team-oriented approach and openness to collaboration across scientific disciplines.

Nice To Haves

• Direct experience with automated peptide synthesizers, specifically Multi Pep and Liberty Prime.
• Experience with high-throughput screening.
• Experience with solid-phase oligonucleotide synthesis, purification, and conjugation; this is not required.

Responsibilities

• Perform peptide synthesis using automated synthesizers, including Multi Pep and Liberty Prime.
• Purify synthesized products using HPLC and analyze them by mass spectrometry.
• Perform in vitro biochemical assays with peptides, oligonucleotides, and proteins.
• Maintain chemistry instruments and supplies.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: No Education Listed