Purification Technician I/II
About The Position
The Purification Technician performs fundamental production tasks in a Good Manufacturing Practice (GMP) environment. The role includes maintaining clean work areas, cleaning and assembling or disassembling equipment according to procedures, assisting with process-control activities, and keeping production records and logs. The technician processes intermediates to isolate target proteins and produce sterile bulk for delivery to filling. Level I work includes housekeeping, preparing cleaning and sanitization reagents, cleaning and sterilizing production equipment, operating production equipment and forklifts, carrying out bulk processing and filtration, preparing buffer solutions, and documenting production activities. Level II work includes the Level I duties as applicable, as well as equipment operation, pH and buffer additions, sample preparation, processing calculations, reagent weighing and preparation, bulk preparation, filtration integrity tests, and identifying mechanical or safety hazards. The position is based in a manufacturing environment and involves rotating 12-hour shifts, with exposure to biological fluids, chemicals, electrical manufacturing equipment, tools, moving machinery, high noise levels, and extreme cold. Personal protective equipment is required. The role requires frequent standing, walking, lifting, carrying, bending, twisting, hand and foot movements, and occasional entry into confined spaces.
Requirements
- High school diploma or equivalent for Level I.
- Basic math and computer skills.
- Mechanical aptitude and attention to detail.
- Ability to work in a team environment and exercise good judgment.
- For Level II consideration, typically at least 12 months as a Technician in the respective department.
- For Level II consideration, a minimum rating of meets expectations overall on the most recent performance review.
- Ability to lift up to 50 pounds and stand or walk continuously during the shift.
- Ability to work rotating shifts.
Nice To Haves
- Bioworks Certificate preferred.
Responsibilities
- Maintain production areas through general housekeeping in accordance with pharmaceutical standards.
- Follow and demonstrate understanding of GMP requirements.
- Safeguard facilities, equipment, product, and coworkers through safe work practices.
- Prepare cleaning and sanitization reagents and clean and sanitize production areas.
- Assemble, disassemble, clean, and sterilize production equipment.
- Operate production equipment, including centrifuges, ultrafiltration units, columns, autoclaves, pasteurizers, and spectrophotometers.
- Operate forklifts safely and efficiently.
- Perform bulk processing and filtration using process parameters such as pH, weights, and suspension.
- Document production activities in real time and maintain accurate records and logs.
- Prepare buffer solutions and properly store process intermediates.
- Isolate target proteins from intermediates, process them to sterile bulk, and deliver them for filling.
- Perform pH and buffer additions and prepare samples.
- Calculate processing requirements and weigh, calculate, prepare, and add required powders, chemicals, and reagents.
- Perform routine operations associated with bulk preparation and pre- and post-filtration integrity tests.
- Recognize and report mechanical and safety hazards to the appropriate individuals.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
High school or GED
