Purification Development Scientist (Philadelphia)
Roche•Philadelphia, PA
•$91,000 - $169,000•Onsite
About The Position
The Downstream Process Development (DSPD) team is seeking a highly motivated Scientist with a specialized focus on filtration processing and relevant biopharmaceutical industry experience. In this role, you will actively participate in advancing multiple innovative downstream process development programs within Roche’s robust pipeline. The successful candidate will drive laboratory execution, contribute to process optimization, and collaborate cross-functionally to support the advancement of breakthrough therapeutics.
Requirements
- Ph.D. in Biochemistry, Chemistry, Chemical Engineering, Bioengineering, or a related discipline with 0–4 years of relevant industry experience; OR M.S. / B.S. in Biochemistry, Chemistry, Chemical Engineering, Bioengineering, or a related discipline with 3–7 years of relevant industry experience.
- Strong foundational knowledge of downstream process development for biologics (e.g., viral vectors, monoclonal antibodies, vaccines, or recombinant proteins).
- Proven experience operating Ultrafiltration/Diafiltration (UF/DF), Tangential Flow Filtration (TFF), and other standard filtration systems.
Nice To Haves
- In-depth theoretical and practical understanding of TFF and advanced filtration operations.
- Working knowledge and purification skills specific to viral vectors or vaccines.
- Familiarity with analytical techniques used for in-process testing and product characterization.
- Previous professional experience utilizing data science tools.
Responsibilities
- Execute laboratory experiments efficiently according to predefined experimental designs, protocols, and timelines.
- Contribute to the troubleshooting, optimization, and scale-up of downstream processes to successfully meet project milestones.
- Maintain comprehensive, accurate, and highly detailed laboratory records.
- Ensure timely closure of experiments and author high-quality technical development reports.
- Support the maintenance of essential laboratory equipment and critical raw material inventories to ensure seamless operations.
- Partner with team members to ensure DSP laboratories are maintained in a safe, professional, and well-organized manner.
Benefits
- Relocation benefits are not available for this position.
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
Upload and Match Resume
What This Job Offers
Job Type
Full-time
Career Level
Entry Level
