Program Manager

Mass General Brigham•Boston, MA

9d•$79,560 - $115,721•Hybrid

About The Position

The Division of Neuropsychiatry and Interventional Psychiatry at Mass General Brigham and Harvard Medical School integrates research, innovation, clinical care, and training across a large and dynamic clinical neuroscience portfolio. Reporting to the Division Chief, the Program Manager for Research Operations will lead the execution and operational infrastructure of the Division’s research portfolio, ensuring that studies, grants, and scientific outputs progress reliably from initiation through completion. This role serves as the operational backbone for research activities, building systems, enforcing timelines, and overseeing day-to-day research operations. The Program Manager partners closely with research staff, faculty, and institutional teams, ensuring high-quality, compliant, and efficient study execution within a structured and scalable operational framework.

Requirements

Degree in life sciences, public health, healthcare administration, or related field
5+ years of experience in human research operations, clinical trials, or research program management
Demonstrated expertise in regulatory compliance and GCP standards
Experience with study management systems (e.g., REDCap, OnCore)
Experience building operational systems (dashboards, workflows, SOPs)
Strong project management, organizational, and leadership skills

Nice To Haves

Project Management Professional (PMP) or equivalent certification.
Certified Research Administrator (CRA), or equivalent certification
Experience in academic medical centers or large research organizations
Familiarity with NIH funding mechanisms and research administration processes

Responsibilities

Oversee study execution across the full research lifecycle, including: protocol development and study start-up active study operations participant enrollment and study visits study closeout and reporting
Directly supervise a team of research assistants and junior staff, including hiring, onboarding, supervision, task allocation, performance management, and professional development.
Ensure appropriate staffing, coverage, and workload allocation across studies.
Provide ongoing coaching and guidance to research staff to support high-quality study execution and day-to-day operational reliability across studies.
Serve as the primary operational point of contact for study teams, resolving day-to-day issues and ensuring smooth coordination across projects
Support preparation and coordination of administrative and regulatory components of grant applications, working with investigators and pre-/post-award teams to ensure completeness, alignment with study operations, and timely submission
Develop and maintain systems to support research operations, including: project and portfolio tracking tools dashboards and reporting frameworks SOPs and standardized workflows
Define and implement metrics to monitor study launch, progress, recruitment, and performance
Maintain structured dashboards and trackers that identify project status, upcoming milestones, risks, and dependencies, and ensure this information is current and actionable
Build scalable infrastructure that can be adopted across the division
Translate research priorities into structured work plans with: timelines ownership deliverables
Track progress across projects and ensure adherence to milestones and deadlines
Identify delays, bottlenecks, and risks early and implement corrective actions
Work closely with investigators and study teams to ensure alignment and execution
Actively enforce follow-through and accountability across research workstreams
Oversee regulatory and compliance processes, including: IRB submissions, amendments, and renewals protocol deviations and reportable events maintenance of required regulatory documentation adherence to Good Clinical Practice (GCP) standards
Implement and maintain quality and compliance systems across studies, including regulatory oversight, data quality assurance, and protocol adherence across studies
Ensure compliance with institutional, NIH, and sponsor requirements
Coordinate with institutional compliance and research administration offices
Ensure research staff maintain required certifications and are appropriately trained in and adhere to Good Clinical Practice (GCP) standards and institutional compliance requirements; monitor compliance and address gaps as needed
Delegate execution of administrative tasks to research assistants or administrative staff and ensure appropriate oversight and completion
Build and maintain systems for: onboarding and training workflows equipment and inventory tracking operational logs and reporting
Ensure reliability, completeness, and efficiency of operational processes
Ensure research operations are executed in accordance with divisional priorities, coordinating with division leadership and relevant functional leads as needed
Coordinate dependencies between research operations and related functions (innovation teams, data/analysis, grants/finance, and executive operations), ensuring timelines and deliverables remain aligned
Ensure research timelines are coordinated with grant submission cycles, data availability, and other operational dependencies
Facilitate communication across teams to resolve operational issues and maintain momentum on shared workstreams