Process Engineer

Biosphere•Oakland, CA
•Onsite

About The Position

Biosphere is seeking a Process Engineer to support the design of its 20 m³ demonstration facility and build and operate pilot-scale UV bioreactors. The work combines process design with hands-on equipment construction and operation. The engineer will develop process design deliverables for the demonstration plant and pipe, instrument, commission, and operate pilot reactors. This is an in-person role at Biosphere’s Oakland, California facility, reporting to the Principal Process Engineer. The title and level (Engineer I, II, or III) will be determined based on experience.

Requirements

  • Bachelor’s degree in Chemical Engineering or a related field such as bioengineering or mechanical engineering.
  • 1 to 6 years of experience in process engineering, process development, or pilot plant/manufacturing operations; new graduates with strong co-op or internship experience will be considered for Engineer I.
  • Strong chemical engineering fundamentals, including mass and energy balances, fluid flow, heat transfer, and pump and line sizing.
  • Ability to read and produce P&IDs.
  • Hands-on experience and comfort using wrenches, assembling sanitary tubing, wiring instruments, or building skids, with interest in further developing those skills.
  • Clear writing, strong communication, organization, and ability to run small projects with minimal oversight.
  • Ability to lift 50 lb, stand for extended periods, and wear PPE.
  • Must be a U.S. citizen or permanent resident due to federal contract requirements.

Nice To Haves

  • Fermentation or bioprocess experience, including sterile design, SIP/CIP, and aseptic operation.
  • Familiarity with hygienic design standards such as ASME BPE and EHEDG.
  • Experience in food and beverage, pharma, specialty chemicals, or an industrial biotech pilot plant.
  • Experience producing or reviewing FEL/FEED packages and/or working with external engineering firms.
  • CAD experience for process documentation, such as AutoCAD Plant 3D, SolidWorks, or similar.
  • Exposure to PLCs, SCADA, and instrumentation.
  • Comfort working in an early-stage company and adapting to uncertainty and evolving priorities as the business grows.

Responsibilities

  • Contribute to demonstration-facility process design deliverables, including the design basis, mass and energy balances, PFDs, P&IDs, equipment lists and specifications, and process control narratives.
  • Size and specify process equipment and utilities, including vessels, pumps, heat exchangers, filtration, piping, valves, and instruments; support vendor selection and quote review.
  • Design, build, and commission pilot-scale UV bioreactors, roughly 100 L to 2 m³, including piping, instrumentation, and basic controls integration.
  • Operate pilot equipment alongside R&D, run fermentation and sterilization tests, collect data, and translate results into design changes.
  • Support design reviews, HAZOPs, FAT/SAT, and commissioning for demonstration-plant equipment.
  • Work with engineering partners, vendors, and fabricators, and review their deliverables.
  • Maintain current documentation, including drawings, specifications, procedures, and test batch reports.
  • Help maintain a safety-first culture in the lab, shop, pilot spaces, and plant.

Benefits

  • Competitive compensation through a mix of salary and equity.
  • Unlimited paid vacation and sick/leave days, plus public holidays.
  • Comprehensive health insurance for employees and their dependents, including dental and vision.
  • Paid family leave.
  • Membership at Pacific Pipe Climbing gym next door.
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