Principal Technical Sub-Project Manager (Drug Product Filling & Compounding Equipment)

Genentech • Hillsboro, OR

1d • $109,900 - $204,100 • Onsite

About The Position

This role is an integral part of our Equipment Engineering team, dedicated to delivering cutting-edge solutions for drug product filling and compounding systems that ensure safe, efficient, and compliant pharmaceutical manufacturing. As a member of this team, you will collaborate with global stakeholders, equipment manufacturers, and multidisciplinary project teams to drive the successful delivery of capital projects. With a focus on innovation, quality, and operational excellence, you will contribute to advancing Roche’s mission of providing life-changing medicines to patients worldwide.
The Opportunity
As a Principal Technical Sub-Project Manager (Drug Product Filling & Compounding Equipment), you will lead and manage the technical execution of drug product filling and compounding equipment sub-projects, driving collaboration across global teams and ensuring compliance with industry standards. You will be accountable for delivering innovative, high-quality solutions that support the manufacturing of Roche’s life-saving medicines. Additionally, you will:

Requirements

• You possess a Bachelor’s Degree in Mechanical Engineering, Chemical Engineering, or a related discipline with 8+ of experience, or a Master’s Degree with 6+ years of experience in pharmaceutical/biopharmaceutical filling and compounding equipment; an MS in Engineering and/or an MBA is preferred.
• You possess extensive years of experience in international management of capital projects related to drug product filling and compounding equipment, with typical project budgets ranging from 15 to 50m CHF.
• You possess 8+ years of specific operational experience with filling and compounding systems and equipment, including aseptic filling, lyophilization, vial/syringe filling, and aseptic compounding systems.
• You have proven experience collaborating with equipment manufacturers, leading FAT/SAT efforts, and managing equipment commissioning and qualification activities.
• You possess significant knowledge with regulatory compliance (FDA, EMA) and GMP requirements for filling and compounding operations, with demonstrated success in delivering complex projects in pharmaceutical manufacturing environments.
• Significant travel (50% +) assignment requiring weekly commuting and/ or temporary remote assignment as required to meet the business need (including on-site presence during FAT/SAT activities). International project assignment of 1 to 3 years as required to meet the business need.

Responsibilities

• Independently plan, design, and implement mechanical and process engineering projects, ensuring full compliance with Roche Guidelines, Global Standards, and Health Authority Requirements.
• Manage the approved sub-project budget and schedule, define priorities, and provide regular updates on progress, risks, mitigation strategies, and escalations.
• Serve as the primary interface with equipment manufacturers, managing technical specifications, design reviews, performance validation, and compliance requirements.
• Lead and coordinate Factory Acceptance Tests (FATs), Site Acceptance Tests (SATs), commissioning, and qualification activities to ensure operational readiness of equipment.
• Direct and manage external engineering firms, service providers, and contractors to ensure timely and quality-compliant project execution.
• Guide overall project scope, including options analysis, project planning, detailed scheduling, and resource allocation.
• Mentor and coach less experienced engineers, fostering technical growth and professional development across the team.

Benefits

• A discretionary annual bonus may be available based on individual and Company performance.
• This position also qualifies for the benefits detailed in this link.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Number of Employees: 5,001-10,000 employees