Principal Site Activation Manager

Syneos Health • Morrisville, NC

2d • $97,300 - $170,300

About The Position

Syneos Health is seeking a Principal Site Activation Manager to lead and oversee global site activation from study start-up through site readiness. The role develops and executes country and site activation strategies, manages timelines, risks, and deliverables across multiple studies or programs, and partners with Clinical Operations, Regulatory Affairs, Contracts & Budgets, and external stakeholders. The manager drives performance metrics and activation milestones, provides guidance and oversight to Site Activation Managers and study teams, supports escalation and resolution of complex start-up challenges, and ensures compliance with regulatory requirements, SOPs, and sponsor expectations.

The company describes a supportive environment focused on career development, training, recognition, inclusion, and quality-of-life balance. Benefits for this position may include a company car or car allowance, medical, dental, and vision coverage, a 401(k) company match, eligibility to participate in an Employee Stock Purchase Plan, eligibility to earn commissions or bonuses based on company and individual performance, and flexible paid time off and sick time. Paid sick time eligibility may vary by location.

Responsibilities

• Lead and oversee global site activation activities from study start-up through site readiness.
• Develop and execute country and site activation strategies.
• Manage timelines, risks, and deliverables across multiple studies or programs.
• Partner with Clinical Operations, Regulatory Affairs, Contracts & Budgets, and external stakeholders.
• Drive performance metrics and ensure activation milestones are achieved.
• Provide guidance and oversight to Site Activation Managers and study teams.
• Support issue escalation and resolution for complex start-up challenges.
• Ensure compliance with regulatory requirements, SOPs, and sponsor expectations.

Benefits

• Company car or car allowance may be available.
• Medical, dental, and vision health benefits.
• Company match 401(k).
• Eligibility to participate in an Employee Stock Purchase Plan.
• Eligibility to earn commissions or bonuses based on company and individual performance.
• Flexible paid time off (PTO) and sick time, subject to applicable location-based eligibility.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: No Education Listed