About The Position

UCB is seeking a scientifically rigorous, collaborative, and results-focused Principal Scientist to join its Translational Medicine and Biomarkers team. The role leads translational biomarker projects connecting drug discovery programs with clinical development. The scientist evaluates mechanisms of action and pharmacokinetic and pharmacodynamic relationships, shapes biomarker strategy in autoimmune disease, and translates complex data into program decisions. The position may be based in Candid offices in San Diego, California, or performed remotely within the United States. It reports to the Executive Director, Translational Medicine and works with Discovery, Clinical Development, Clinical Pharmacology, and Clinical Operations colleagues, as well as contract research organizations, external collaborators, and scientific stakeholders. The role is full-time and may require travel up to 10%.

Requirements

  • Doctorate in immunology, rheumatology, molecular biology, or a related field.
  • At least 4 years of biotechnology or pharmaceutical biomarker-development experience.
  • Proven knowledge of autoimmune disease biology and translational molecular technologies.
  • Validated experience developing qualified flow cytometry panels with external research partners.
  • Demonstrated project leadership, organization, and milestone-tracking skills.
  • Fluency in written and spoken English.
  • Willingness to travel up to 10%.

Nice To Haves

  • Experience with T-cell engagers or bispecific antibody therapeutics.
  • Experience with preclinical biomarkers and disease models.
  • Experience with single-cell RNA sequencing or immune-repertoire sequencing.
  • Proficiency in data analysis and visualization using R, Python, or similar tools.
  • Ability to thrive independently in a fast-paced, entrepreneurial environment.

Responsibilities

  • Lead biomarker projects supporting preclinical and clinical program decisions.
  • Develop translational hypotheses for treatment response and non-response.
  • Shape translational research strategy for autoimmune disease programs.
  • Interpret and present biomarker data to internal and external stakeholders.
  • Guide assay development and study-sample oversight with external research partners.
  • Support translational content for clinical and regulatory documents.

Benefits

  • Supportive culture emphasizing inclusion, respect, and equal opportunities.
  • Opportunities for professional growth and freedom to develop a career path.

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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