Principal Scientist

Waters Corporation•Milford, MA

1d•$119,000 - $198,000

About The Position

Waters Corporation seeks an innovative and highly motivated Principal Scientist to join the Core Separation Team within the Chemistry & Lab Automation (C&LA) Business Unit. In this role, you will advance liquid chromatography (LC) science by evaluating, developing, and commercializing next-generation chromatographic technologies. As a technical leader, you will collaborate across R&D, engineering, materials science, applications, and product management to transform innovative concepts into successful products. The ideal candidate combines deep expertise in liquid chromatography with strong scientific leadership and problem-solving skills. This role will help shape future LC column technologies and chromatographic media that deliver meaningful value to customers worldwide.

Requirements

Ph.D. in Chemistry, Biochemistry, Chemical Engineering, or a related field with 5+ years of industrial experience, including leadership of technical projects; or an M.S. degree with 7+ years of relevant industry experience.
Strong knowledge of liquid chromatographic theory, separation mechanisms, and stationary-phase chemistry.
Hands-on expertise in liquid chromatography, including the use of mass spectrometric detection.
Proven experience developing, optimizing, and troubleshooting LC methods.
Proficiency with HPLC instrumentation, laboratory operations, and instrument maintenance.
Demonstrated ability to independently lead technical programs and manage multiple priorities.
Excellent written and verbal communication skills, including experience in giving technical presentations and writing scientific report.
Strong analytical thinking, scientific curiosity, and commitment to innovation.
Ability to collaborate and influence effectively across multidisciplinary teams.

Nice To Haves

Experience developing or characterizing chromatographic columns, stationary phases, or separation media.
Experience supporting product development, manufacturing transfer, commercialization, or quality-control activities.
Knowledge of analytical workflows in pharmaceutical, biopharmaceutical, environmental, food, or related industries.
Track record of patents, publications, invention disclosures, or scientific presentations.
Experience applying Design of Experiments (DOE) and data-driven approaches to technology development.

Responsibilities

Design and execute experiments to evaluate novel LC columns, stationary phases, and sample preparation devices for small-molecule separations.
Provide technical leadership for cross-functional development programs involving chromatographic science, applications, and method development.
Collaborate with engineering, materials science, and product teams to develop hypotheses, design studies, and optimize emerging technologies.
Lead laboratory characterization and performance testing of prototype column products and sample preparation devices, assessing efficiency, robustness, reproducibility, and application suitability.
Prepare reports and provide internal presentations to summarize scientific findings
Develop and optimize chromatographic methods supporting technology evaluation, product development, and customer applications.
Establish analytical methods, product specifications, and quality-control procedures for product launch.
Drive the transition of new technologies from research through development, manufacturing, and product launch.
Contribute to intellectual property generation by assisting with invention disclosures and patent applications.
Work with marketing colleagues and other technical groups across Waters to successfully commercialize new products and to showcase them through publications and presentations at conferences
Monitor scientific and competitive trends to identify emerging applications, methods and customer needs.
Maintain laboratory operations and ensure compliance with environmental, health, safety, and quality (EHSQ) requirements.