Principal Scientist, Process Chemistry

Pharmaron • Coventry, RI

3d • Onsite

About The Position

We are seeking an experienced and collaborative Principal Scientist to lead complex chemical development programs within a fast-paced Process Chemistry environment. This role provides scientific leadership across multidisciplinary project teams, supporting API development for GLP toxicology studies and GMP clinical manufacturing while delivering high-quality solutions to clients. The successful candidate will combine strong technical expertise in synthetic/process chemistry with leadership, mentoring, and client-facing responsibilities.

Requirements

• PhD in Chemistry or related field with 7–15 years of relevant industry experience OR MSc in Chemistry or related field with 11–20 years of relevant industry experience
• Strong background in process chemistry, chemical development, and API development within pharmaceutical or biotechnology environments
• Expertise in retrosynthetic analysis and advanced laboratory techniques supporting process optimization and scale-up activities
• Demonstrated success solving complex scientific challenges across development programs
• Experience supporting API drug development within regulated environments
• Strong understanding of GLP/GMP principles and regulatory expectations preferred
• Proven ability to lead scientific initiatives and collaborate effectively across multidisciplinary teams
• Previous mentoring, project leadership, or people leadership experience preferred
• Strong communication and client-facing skills

Responsibilities

• Lead and design experimental programs to solve complex chemical development challenges for client projects and internal initiatives.
• Apply advanced process chemistry and retrosynthetic analysis expertise to support API development and process optimization.
• Plan, execute, document, and report experimental work in compliance with applicable GxP, ICH, GMP, and company standards.
• Serve as a scientific leader and mentor to junior scientists and cross-functional project teams.
• Manage and support multiple client projects, including project leadership, reporting, technical discussions, and delivery of project milestones.
• Support technology transfer activities and mixed-model projects across the organization.
• Build strong client relationships, host client visits, and support internal and external audits.
• Stay current with emerging scientific technologies and apply innovative approaches to process chemistry challenges.
• Promote a strong quality culture, collaboration, safety, and continuous improvement within the department.
• Maintain accurate training records and ensure compliance with all safety, procedural, and environmental requirements.

Benefits

• Insurance including Medical, Dental & Vision with significant employer contributions
• Employer-funded Health Reimbursement Account
• Healthcare & Dependent Care Flexible Spending Accounts
• 100% Employer-paid Employee Life and AD&D Insurance, Short and Long Term Disability Insurance
• 401k plan with generous employer match
• Access to an Employee Assistance Program

What This Job Offers

• Job Type: Full-time
• Career Level: Principal