Principal Scientist - Analytical Research and Development

Pfizer • Bothell, WA

11h • Hybrid

About The Position

As a Principal Scientist, you will be at the center of our operations, and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be recognized as a technical expert and a significant scientific contributor. With your deep knowledge of the discipline, you will regularly contribute to the therapeutic area level and can represent the department on multidisciplinary teams. With your deep knowledge of the discipline, you will work with internal and external partners around the world to manage and oversee GMP analytical readiness for novel small molecule components for use in targeted therapeutics. You will use strong communication skills to ensure technical and business line alignment across a variety of stakeholders within multidisciplinary teams. It is your scientific diligence, knowledge, and focus on execution that will help in making Pfizer ready to achieve new milestones and help patients across the globe. You will play a lead role in establishing an outsourcing culture and mindset within ARD.

Requirements

• Ph.D. in Analytical Chemistry or related field with 4+ years of R&D experience OR Masters in Analytical Chemistry or relevant industry experience with 9+ years of R&D experience, OR B.S. with 12+ years of relevant industry experience and analytical development experience.
• Significant hands-on experience of the development and application of common analytical methods to support the progression of drug candidate development workflows.
• Good Knowledge of the development workflows used by ARD’s key partners within PSSM.
• Demonstrated ability to manage parallel projects, prioritize activities in a dynamic environment, meet timelines, and interact with multidisciplinary teams and stakeholders.
• A breadth of diverse leadership experiences and the ability to lead change and work in new paradigms.
• Attention to detail, strong organizational skills, and effective interpersonal and communication skills are required.
• Demonstrated oral and written communication skills, including visualization of data, presentations, and authoring technical articles
• Demonstrated ability to meet timelines and interact with multi-disciplinary teams.
• Demonstrated ability to learn new techniques and solve complex analytical problems.
• Demonstrated ability to work with contract manufacturing organizations.
• Proficient with a wide variety of software and information systems.
• Good understanding of GMP as applied to analytical development.
• Permanent work authorization in the United States.

Nice To Haves

• Relocation assistance may be available based on business needs and/or eligibility.

Responsibilities

• Collaborate with project teams, development analysts, GMP analysts and external vendors to deliver multiple units of analytical work in parallel.
• Manage analytical testing through successful, timely delivery for internal project teams in support of small molecule drug development.
• Apply expertise in separations and chromatography as well as other analytical methodologies to enable drug development utilizing external resources.
• Independently deliver technical work packages in support of drug development during all clinical phases.
• Focus on analytical development activities including validating and transferring analytical methods, developing, and executing general testing protocols aligned with ARD development workflows, critically evaluating vendor generated data and compiling summaries as required.
• Collaborate with ARD colleagues to identify appropriate analytical approaches, ensuring vendors clearly understand Pfizer's needs, managing technical risks, and developing appropriate contingencies across a dynamic portfolio.
• Directly interact with outsourcing colleagues in partner groups and therefore requires knowledge of API and DP development workflows.
• Manage differences in analytical instrumentation and operating procedures between the vendors and Pfizer, ensuring minimal technical impact on the work packages and data being delivered.
• Capture relevant feedback and facilitate the evolution of best practices and process improvements with the vendor.

Benefits

• 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution
• paid vacation, holiday and personal days
• paid caregiver/parental and medical leave
• health benefits to include medical, prescription drug, dental and vision coverage.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: Ph.D. or professional degree