Scientist, Analytical Development

Moderna • Norwood, MA

6h • Onsite

About The Position

Moderna is seeking a Scientist to join the Analytical Development team in Norwood, MA. This individual will play a critical role in developing, optimizing, and implementing advanced analytical methods that support Moderna’s expanding therapeutic and vaccine portfolio. The successful candidate will generate high-quality data to drive method development, process understanding, and analytical readiness across new programs and manufacturing platforms. The ideal candidate is hands-on, detail-oriented, and thrives in a collaborative, fast-paced environment. This role requires strong technical skills in chromatography, spectroscopy, and separation sciences, along with the ability to manage multiple projects and communicate effectively with cross-functional partners in Analytical Development, Process Development, and Quality.

Requirements

• PhD degree with 0-2 years or MS degree with 5+ years of relevant industry experience in Analytical Chemistry, Biochemistry, Chemistry, or related discipline.
• 4-5 years hands-on experience in LC-MS, HPLC, UV/Vis, spectroscopy, MAM workflows.
• Proficiency in software tools for MS data analysis (Xcalibur, MassHunter, Skyline, Biopharma Finder, Protein Metrics)
• Proven ability to perform method development, troubleshooting, and data analysis in support of biologics, RNA, or complex formulations.
• Familiarity with regulatory guidance, method transfer, and collaboration with Quality in a regulated environment is required.
• Strong technical writing and documentation skills.
• Excellent organizational and multitasking ability in a fast-paced environment.
• Demonstrated collaboration and communication skills to work effectively with cross-functional teams.
• Highly motivated, scientifically curious, and capable of working independently with minimal supervision.

Nice To Haves

• Familiarity with LNP characterization or nucleic acid-based analytical methods

Responsibilities

• Develop and execute analytical methods, including mass spectrometry and HPLC with various detector configurations, to assess Moderna’s plasmid, mRNA, and LNP-based products.
• Perform intact mass analysis and primary structure characterization of proteins.
• Develop LC-MS/MS methods for qualitative and quantitative protein analysis.
• Generate feasibility data and support method development and optimization for novel platforms, including new plasmid manufacturing approaches and oncology programs.
• Collaborate cross-functionally with Research Analytics, Process Development, Quality Control, and Analytical Technical Operations to support method development, qualification, investigations, and technology transfer.
• Document experimental work in electronic lab notebooks and author technical reports, summaries, and method implementation documents.
• Maintain and troubleshoot LC-MS instrumentation, including Orbitrap, Q-TOF, and triple quadrupole systems.
• Maintain a strong focus on quality and data integrity, ensuring compliance with internal standards and regulatory expectations.

Benefits

• Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investment opportunities to help you plan for the future
• Location-specific perks and extras
• The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 1,001-5,000 employees