About The Position

Cyprotex US, an Evotec company, is seeking a Principal Scientist - ADMET Study and Innovation Manager to lead the delivery of partner and client ADMET studies throughout their full lifecycle, from proposal development and pricing through quality review, data delivery, and final sign-off. The role provides scientific leadership, drives innovation initiatives, and supports continuous improvement across the Project Management group. It works closely with Business Development, Project Managers, Heads of Function, scientific teams, clients, and external partners to ensure an excellent client experience, operational excellence, and adoption of innovative solutions. The position includes leading study delivery and client scientific support; reviewing routine ADME and toxicology data; providing technical direction for customised assays and complex study designs; evaluating and implementing emerging technologies and methodologies; and supporting proposals, pricing, study plans, work orders, and technical solutions. The role also contributes to commercial performance monitoring, accurate CRM and LIMS records, revenue reporting, process improvement, colleague development, and a collaborative team culture. The successful candidate must maintain compliance with applicable health, safety, quality, and regulatory requirements and complete related training and administrative responsibilities. This is a hybrid role based in Princeton, New Jersey, with 3–5 business days per month on site. The position is salaried and exempt, with a stated base pay range of $134,000 to $155,000. Additional total rewards include a discretionary annual bonus, medical, dental and vision coverage, short- and long-term disability, company-paid basic life insurance, a 401(k) company match, paid time off and holidays, and wellness and transportation benefits.

Requirements

  • Bachelor's, Master's, or PhD degree in Biology, Chemistry, Pharmacology, Toxicology, or a related life science discipline.
  • At least five years of relevant industry experience.
  • Evidence of leadership in study management, innovation initiatives, or strategic program delivery.
  • Relevant experience in the pharmaceutical, biotechnology, CRO, or drug discovery sectors.
  • Strong understanding of ADMET principles, assays, toxicology, high-throughput screening, and their application to drug discovery and development.
  • Project, study, or client management experience in a scientific environment.
  • Experience supporting client interactions, proposal development, study design, and scientific consultation.
  • Excellent written, verbal, presentation, and stakeholder management skills.
  • Customer-focused approach and ability to build trusted internal and external relationships.
  • Strong problem-solving skills, resilience, and ability to navigate complex scientific and operational challenges.
  • Proactive, solutions-oriented approach and a record of delivering results and driving improvements.
  • Excellent organisational skills and attention to detail.
  • Ability to manage multiple priorities while maintaining quality and responsiveness.
  • Strong interpersonal and networking skills for collaboration across multidisciplinary teams.
  • Adaptability and a positive approach to changing priorities and evolving business needs.

Nice To Haves

  • Experience contributing to innovation, process improvement, technology implementation, or scientific capability development.

Responsibilities

  • Lead and manage partner and client ADMET studies, ensuring requirements are communicated clearly and studies are completed efficiently, on time, and to specification.
  • Serve as a primary scientific contact for clients, providing expert guidance, data interpretation, and strategic recommendations.
  • Review and quality-check routine ADME and toxicology study data against established quality standards.
  • Provide technical leadership for customised assays, complex study designs, and challenging scientific enquiries.
  • Coordinate information, materials, and compounds among internal teams, clients, and external partners throughout the study lifecycle.
  • Anticipate and resolve scientific, operational, and logistical challenges that could affect study outcomes or timelines.
  • Champion innovation initiatives that enhance scientific capabilities, operational efficiency, and competitive advantage.
  • Identify, evaluate, and support implementation of emerging technologies and methods, including NAMs, organ-on-a-chip systems, in vitro modelling technologies, and digital solutions.
  • Collaborate with scientific and operational leaders to define and execute innovation roadmaps aligned with business objectives and client needs.
  • Support proposals, pricing strategies, study plans, work orders, and technical solutions with Business Development and technical teams.
  • Represent the organisation in internal and external meetings, offering scientific and technical expertise to clients, collaborators, and strategic partners.
  • Contribute to thought leadership, internal knowledge sharing, process development, and identification of future service opportunities.
  • Develop relationships with existing and prospective clients and partners and support customer satisfaction and repeat business.
  • Monitor study opportunities, revenue trends, and commercial performance metrics.
  • Maintain accurate and timely CRM, LIMS, and associated tracking-system records to support forecasting, invoicing, and revenue recognition.
  • Work with Finance and Commercial teams on monthly revenue reporting and study reconciliation.
  • Identify and support process improvements that increase productivity, operational efficiency, customer experience, quality, throughput, and profitability.
  • Coach, mentor, and support Study Management colleagues in their professional and technical development.
  • Foster an inclusive, collaborative, accountable, and high-performing team culture and build cross-functional relationships.
  • Model company values and behaviours, demonstrating professionalism, integrity, and commitment to excellence.
  • Maintain compliance with applicable health, safety, quality, and regulatory requirements; complete mandatory training and keep training records.
  • Identify development needs and agree objectives with the manager; complete timesheets and other administrative requirements accurately and on time.
  • Participate in performance management and development processes, including Evotalks and objective setting.
  • Undertake other duties reasonably requested that are consistent with the level and scope of the role.

Benefits

  • Professional courses, mentorship, and new projects to support learning and development.
  • Flexible work options and a hybrid arrangement with 3–5 business days per month on site.
  • Inclusive work environment where diverse voices and curiosity are valued.
  • Opportunity to work on innovative projects and cutting-edge technology.
  • Discretionary annual bonus.
  • Medical, dental, and vision benefits.
  • Short-term and long-term disability coverage.
  • Company-paid basic life insurance.
  • 401(k) company match.
  • Paid time off and paid holidays.
  • Wellness and transportation benefits.
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