Principal Research Associate, Antibody Discovery (Immunology)

Adimab•Lebanon, NH

About The Position

Adimab is the leading technology provider for therapeutic antibody drug discovery, focusing solely on our partnerships without pursuing an internal product pipeline. Since 2009, we have partnered with over 140 pharmaceutical and biotechnology companies, generating more than 650 therapeutic programs, of which more than 85 have entered clinical trials. We are seeking an experienced, self-motivated, and enthusiastic biologist/bioengineer to join our Antibody Discovery immunology team. The Principal Research Associate will work in a small, collaborative team to execute and advance Adimab’s in vivo antibody discovery and optimization platform against challenging targets. This role will closely interface with a variety of internal Adimab teams and work closely with external drug discovery partners. The successful candidate will have prior experience in immunology, biotechnology, and flow cytometry.

Requirements

B.S. or M.S. in immunology, molecular biology, biological engineering, cellular biology, or a closely related field with 4+ year(s) experience in an academic or industry setting
Demonstrated experience with basic laboratory techniques (e.g. PCR, stoichiometric calculations, molecular cloning, sterile sample handling, sterile tissue culture, flow cytometry)
Demonstrated ability to evaluate, interpret, and present scientific data with a mastery of Microsoft Excel and Powerpoint
Familiarity with the basic concepts of immunology and antibody responses
Excellent organization skills, problem-solving skills, and attention to detail
Self-directed with a proven track record of executing independently at the bench and driving projects to completion
Adaptable and productive in a fast-paced environment
Effective communication skills with the ability to speak openly with colleagues and supervisors
Demonstrated success working within a team and collaborating with multiple groups in an organization

Nice To Haves

Significant previous experience with standard immunological assays (e.g. ELISA, flow cytometry), single-cell RT-PCR, and immune or synthetic library building and selection, would distinguish a highly qualified candidate
Significant yeast handling and antibody engineering background
Experience with the design and execution of mammalian immunization strategies

Responsibilities

Basic handling and culture of yeast and mammalian cells
Murine and human lymphocyte sample handling and characterization
Primary B cell isolation using fluorescence activated cell sorting (FACS)
Collecting, organizing, analyzing, data for a variety of internal and external presentations
Interpreting antibody characterization data
Construction and selection of yeast antibody libraries
Mammalian cell-based characterization assays
Quantification of antibody and B cell responses
Single-cell RT-PCR
Tracking and upkeep of lab reagents and stocks
Collaborating effectively with internal departments and external partners