Principal Engineer, Algorithm - ECG
About The Position
The Principal Engineer, Algorithm – ECG is a senior technical leader responsible for the architecture, development, and advancement of electrocardiogram (ECG) signal processing algorithms that enable accurate, reliable cardiac monitoring in Masimo’s non-invasive platforms. This role drives innovation in ECG-based measurement, including heart rate, rhythm analysis, and advanced cardiac insights, translating complex physiological signals into clinically actionable outputs. The Principal Engineer partners closely with cross-functional teams across hardware, software, systems, and clinical domains to deliver high-performance, regulatory-compliant solutions from concept through commercialization.
Requirements
- 12+ years of relevant experience in ECG algorithm development, signal processing, or related domain
- Deep expertise in ECG signal processing, digital signal processing, and statistical modeling
- Proven experience developing ECG algorithms, including waveform detection and cardiac feature extraction
- Strong programming skills in C/C++, MATLAB, Python, or similar
- Experience working with large-scale physiological or clinical datasets
- Demonstrated ability to translate complex signal processing challenges into robust, real-time solutions
- Strong problem-solving, analytical, and cross-functional collaboration skills
- Ability to work onsite Monday - Friday in Irvine, CA
- Ability to read, write, and communicate effectively in English
- Ability to interpret technical documents, schematics, and written instructions
- Ability to clearly document technical findings and communicate with cross-functional team members
Nice To Haves
- Experience with arrhythmia detection/classification algorithms or cardiac monitoring systems
- Knowledge of cardiac physiology and electrophysiology principles
- Experience applying machine learning techniques to ECG or time-series physiological data
- Familiarity with wearable or ambulatory ECG systems and associated signal challenges
- Experience supporting regulatory submissions (e.g., FDA 510(k), CE Mark)
- Prior contributions to patents, publications, or clinically validated products
Responsibilities
- Lead the design and development of advanced ECG signal processing algorithms, including filtering, feature extraction, waveform delineation, and rhythm classification
- Architect scalable algorithm frameworks for ECG analysis, supporting real-time embedded implementation and cloud-based analytics where applicable
- Develop and optimize algorithms for heart rate detection, arrhythmia identification, and ECG morphology analysis
- Design and conduct validation strategies using clinical datasets to ensure algorithm accuracy, robustness, and generalizability across diverse patient populations
- Address signal quality challenges, including motion artifact, noise reduction, and low-perfusion or ambulatory conditions
- Partner with hardware and systems teams to ensure optimal signal acquisition and end-to-end system performance
- Collaborate with software and firmware teams to implement algorithms on embedded platforms with real-time constraints
- Translate clinical and regulatory requirements into algorithm design inputs, ensuring compliance with applicable standards (e.g., FDA, IEC)
- Establish best practices for algorithm verification, validation, and documentation in regulated environments
- Provide technical leadership and mentorship to engineers, contributing to team capability building
- Drive innovation and contribute to intellectual property, including patents and technical publications
Benefits
- 15% annual bonus based on company, department, and individual performance
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What This Job Offers
Job Type
Full-time
Career Level
Senior
