Principal Associate Scientist
Ascidian Therapeutics•Boston, MA
•Onsite
About The Position
Principal Associate Scientist sought by Ascidian Therapeutics, Inc. to design, validate, execute, and interpret experiments to improve therapeutic performance of designer RNA editing molecules & contribute to characterization of drug candidates to support Ascidian’s Roche Collaboration.
Requirements
- Master’s Degree in Molecular/Cellular Biology, Biochemistry or related field and 3 years relevant experience OR Bachelor’s Degree and 5 years relevant experience
- Experience in RNA therapeutics with a focus on pre-mRNA splicing and protein translation
- Designing and cloning RNA exon-editing molecules
- Designing assays to measure RNA editing
- Optimization and preparation of custom Illumina libraries
- Bioinformatic analysis of the libraries
- Cell culture
- ddPCR, qPCR and protein extraction and characterization by JESS and western blot
- Sanger sequence analysis
- Use of sequence design and software
Responsibilities
- Design, validate, execute, and interpret experiments to improve therapeutic performance of designer RNA editing molecules
- Contribute to characterization of drug candidates to support Ascidian’s Roche Collaboration
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What This Job Offers
Job Type
Full-time
Career Level
Principal
