Principal Administrative Business Partner – Rare Disease

GenentechDaly City, CA
$90,000 - $167,000Hybrid

About The Position

The Principal Administrative Business Partner for the Rare Disease (RD) Squads, supporting Rare Blood Disorders (RBD) and Neurological Rare Diseases (NRD), will serve as a strategic operational anchor within U.S. Commercial, Medical, and Government Affairs (CMG). This high-impact role provides executive administrative partnership to the RD Squad Leader, Chief of Staff, and broader squad teams driving commercialization strategies for life-changing therapies. The role requires balancing autonomy, organizational savvy, and operational excellence while actively contributing to the Commercial Portfolio Organization (CPO) Operations and Administration Community.

Requirements

  • An average of 5–10 years of related administrative, operations, or project management experience supporting senior leadership teams.
  • Proven track record of handling highly confidential and proprietary business information with the utmost discretion and integrity.
  • Demonstrated mastery in independently prioritizing, planning, and executing complex workflows, large-scale events, and project initiatives across matrixed organizations.
  • Advanced fluency with enterprise productivity and collaboration tools (including Google Workspace, gMail, gCal, gSheets, gSlides, gMeet, as well as Zoom and digital site builders).
  • A Bachelor’s degree (BS/BA) or equivalent industry experience.

Nice To Haves

  • Prior administrative or operational experience within the biotechnology or pharmaceutical industry.
  • Previous experience navigating the Genentech or Roche enterprise network, culture, and matrixed operating models.
  • Demonstrated experience training, mentoring, or instructing peers on productivity tools, systems, and standardized administrative processes.
  • Background in supporting commercial, medical, or regulatory affairs squads within rare diseases or specialty therapeutic areas.

Responsibilities

  • Proactively manage complex executive calendars across domestic and international time zones, exercising astute judgment to balance high-priority business demands, confidential matters, and stakeholder access.
  • Partner closely with Squad Operations to design, organize, and execute operational cadences, including drafting rolling agendas, prepping executive materials, and leading large-scale offsites, national field meetings, and departmental workshops.
  • Lead and implement internal engagement and communications strategies, drafting executive communications, overseeing digital collaboration hubs (gSites, newsletters), and maintaining team alignment.
  • Serve as a central connector and project lead across cross-functional teams, managing vendor/speaker contracts, RFP processes, invoices, and purchase orders with rigorous resource sensitivity.
  • Drive team operational health and culture by spearheading space planning initiatives, leading full-cycle onboarding logistics for new hires, and serving as a trusted thought partner on team engagement and pulse checks.
  • Actively pilot and champion modern digital tools, workflows, and best practices across the CPO Administration community to foster a continuous learning and improvement environment.

Benefits

  • A discretionary annual bonus may be available based on individual and Company performance.
  • Benefits detailed at the link provided below.
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