Postdoctoral Researcher, ML for Biology, Hsu Lab

Arc Institute • Palo Alto, CA

3d • Onsite

About The Position

The Hsu Lab is looking for postdoctoral researchers who are curious, creative, and motivated to advance the state-of-the-art in generative AI applied to biology, including Arc’s frontier biological foundation models (Evo, Evo 2, State, Stack, Bioreason, and beyond). The successful candidate is passionate about developing ML models for biological understanding and design, leveraging frontier approaches such as novel ML architectures, post-training, agentic reasoning, and more. Current areas of interest of the lab include building predictive models of life (e.g. by integrating Evo and State), AI agents and systems, genome mining, and invention of new therapeutics through AI-guided approaches. Postdocs in the lab are encouraged to lead ambitious, independent projects, resulting in high-impact publications. You will have the opportunity to collaborate widely across Arc, Stanford, and the broader Bay Area ecosystem, with access to strong platforms in our lab and our institutions for genomics, single-cell technologies, synthetic biology, high-performance computing clusters, and experimental model systems.

Requirements

• Ph.D. in Computer Science, Bioinformatics, Computational Biology, Genetics/Genomics
• Expertise with Python, bash, and standard deep learning frameworks such as PyTorch.
• Excellent written and verbal communication skills.
• Demonstrated ability to work in a fast-paced environment and be both an independent thinker and a highly collaborative team player.
• Track record of creative, high-impact research as demonstrated by publications, patents, developed tools, software etc.

Nice To Haves

• Extremely Curious & Self-Motivated: You push the boundaries of machine learning, biotechnology, and/or biomedical research.
• High-Velocity Researcher: You thrive in a fast-paced environment and have a bias for action, conducting rigorous and impactful research at scale.
• Intellectually Independent: You are a "first-principles" thinker, able to design new research directions and projects.
• Technical Polyglot: You are comfortable (or eager to become so) at the intersection of ML and computational biology, and eager to collaborate with wet-lab scientists.
• Puzzle Solver: You are excited by solving puzzles that have a translational impact and/or creating new therapeutic approaches.

Responsibilities

• Conduct high-impact research: Design, execute, and analyze computational experiments; take end-to-end ownership of a research project within the lab’s scientific focus, with guidance from the PI and increasing independence as you develop expertise.
• Develop as a future scientific leader: Publish first-author papers in high-impact journals, present at national and international conferences, and build a network of collaborators across Arc, Stanford, and beyond.
• Foster scientific excellence: Mentor and train research associates, technicians, and students; engage in Arc-wide activities (seminars, symposia); contribute to a collaborative research environment; maintain rigorous coding standards and documentation; and contribute to lab operations including software development and maintaining shared infrastructure.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree