Postdoctoral Research Associate - Bone Marrow Transplantation and Cellular Therapy
About The Position
A postdoctoral research associate position is available in Dr. Senthil Bhoopalan’s lab, which studies human hematopoiesis in health and disease and develops curative therapies for blood disorders. The research focuses on bone marrow failure disorders, which can cause severe illness and death in children and have limited treatment options. The lab uses disease models including induced pluripotent stem cell-derived hematopoietic stem cells and engineered hematopoietic stem cells to model patient mutations and develop gene therapies. The position will contribute to individualized genome-editing treatments using base editors and prime editors, and to DRIVE (Delivering Rare-disease In Vivo Editors), a translational project funded by ARPA-H. DRIVE aims to develop preclinical models and pipelines to demonstrate the efficacy and safety of in vivo genome editing and accelerate personalized genomic medicines for disorders such as Diamond-Blackfan anemia and GATA2 deficiency. The postdoctoral associate will work with a multidisciplinary team spanning genome editing, high-throughput screening, hematology, cell biology, LNP formulation, technology development and commercialization, cGMP practices, technical writing, regulatory affairs, clinical trial design, and project management. The lab offers access to technical expertise and collaborative opportunities, as well as opportunities to lead projects, learn grantsmanship, and develop a path toward independent research. St. Jude provides shared research resources and facilities, professional and career development programs, and a postdoctoral community. The position is full-time, based in Memphis, Tennessee, and scheduled for 40 hours per week on a weekday day shift. Starting salary is $72,530 per year, with comprehensive benefits and relocation assistance.
Requirements
- PhD.
- Experience working with mice.
- Strong background in cell biology and hematopoietic stem cell (HSC) biology.
Nice To Haves
- Exposure to high-throughput screens.
- Exposure to CRISPR/Cas9.
- Exposure to base editors.
Responsibilities
- Develop novel research projects and ideas in collaboration with a mentor.
- Design and perform experiments, interpret data, and communicate results with the scientific community.
- Work with mouse models of human disease.
- Collaborate with a multidisciplinary team and with collaborative laboratories inside and outside St. Jude.
- Generate initial drafts for grants and research manuscripts.
- Participate in professional development, including grant writing.
Benefits
- Comprehensive benefits.
- Generous relocation assistance.
- Professional development allowance.
- Access to grant-writing workshops, individual development plans, teaching and mentoring opportunities, and non-research career advancement programs.
- Access to shared research resources and facilities led by expert scientists.
- Supportive postdoctoral community.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Education Level
Ph.D. or professional degree
