Postdoctoral Research Associate - Pulmonary & Critical Care Medicine

Washington University in St. Louis • St. Louis, MO

1d • Onsite

About The Position

A postdoctoral position is available immediately at the laboratory of Dr. Choudhury in the Department of Medicine, Division of Pulmonary & Critical Care Medicine at WashU in St. Louis. The Choudhury lab investigates the cellular, molecular, and metabolic mechanisms involved in the development of fibrotic disorders, including idiopathic pulmonary fibrosis, using novel mouse models and human precision-cut lung slices to study how metabolic networks may reveal disease- and context-specific targets for selectively interrupting pathological cellular functions and how these metabolic adaptations may be targeted therapeutically. Our research employs cell signaling and metabolism, fibroblast-immune cell crosstalk, metabolomics, mitochondrial biology, molecular and cellular biology, genetically modified mice, lung fibrosis models, single-cell RNA sequencing, and epigenetics. We are seeking a highly motivated postdoctoral candidate with prior experience in biochemistry and cell and molecular biology; a background in immunology and expertise in flow cytometry and cell sorting and single-cell RNA sequencing are strongly preferred. The ideal candidate will be self-motivated, collaborative, and eager to contribute to complex research studies, experiments, and assays in a supportive environment that values teamwork, dedication, and curiosity. This position also offers the opportunity to develop exciting, cutting-edge independent translational research projects at the intersection of metabolism and cell signaling.

Requirements

• Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree.
• Prior experience in biochemistry and cell and molecular biology.

Nice To Haves

• Background in immunology.
• Expertise in flow cytometry and cell sorting.
• Expertise in single-cell RNA sequencing.
• Recent PhD in Biochemistry, Cell or Molecular Biology with background in immunology.
• Hands-on experience with mouse work and knockout mouse models.
• Excellent written and verbal communication skills.
• Ability to work independently on research projects designed by a mentor within area of specialization.
• Hands-on experience with flow cytometry and cell sorting, fluorescence and confocal imaging, standard biochemistry, molecular/cell biology techniques, cell culture, flow cytometry, data acquisition and data analysis, gene expression, single cell RNAseq/bioinformatics analysis.
• Strong publication record in peer-reviewed journals.

Responsibilities

• Designs and performs experiments.
• Keeps appropriate experimental records and documentation.
• Analyzes, interprets, summarizes, and compiles data.
• Operates and maintains relevant animal models.
• Participates in publications and presentations as an author or co-author.
• Develops proficiency in career development skills, including writing, public speaking, networking, and critical evaluation of scientific literature.
• Maintains conformity with ethical standards in research.
• Assists in preparation of grant proposals and may also apply for mentored training grant with PI support.
• Collegial conduct towards co-trainees, staff members and members of the research group.

Benefits

• Comprehensive and competitive benefits package

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree