Postdoctoral Research Associate - Chemical Biology and Therapeutics - Cupido Lab
About The Position
The Cupido Lab at St. Jude Children’s Research Hospital is seeking a motivated, biology-inclined synthetic chemist to advance RNA proximity-induced pharmacology. The role focuses on discovering, designing, and developing small-molecule modulators using novel screening and compound-optimization platforms, with emphasis on pathways and biological mechanisms that regulate RNA biology and gene expression in cancer and have not yet been drugged. The project is based in the Department of Chemical Biology and Therapeutics and builds on St. Jude’s infrastructure for high-throughput chemical discovery and synthesis. The position offers access to staffed facilities and a collaborative research environment, with opportunities to develop expertise across chemical biology, structural, cellular and molecular biology, proteomics, and drug discovery, as well as to grow through publication, grant writing, collaboration, and career development.
Requirements
- Ph.D. in chemistry, chemical biology, or a related field.
- Familiarity with multistep organic synthesis.
- At least one first-author peer-reviewed publication, accepted or close to being accepted.
Responsibilities
- Discover, design, and develop small-molecule modulators using screening and compound-optimization platforms.
- Investigate pathways and biological mechanisms regulating RNA biology and gene expression in cancer.
- Conduct research in RNA proximity-induced pharmacology within the Department of Chemical Biology and Therapeutics.
Benefits
- Access to state-of-the-art, fully staffed facilities for chemistry, biophysics, biochemistry, structural biology, mass spectrometry, genomics, cell microscopy, and data-driven discoveries.
- A highly collaborative and supportive research environment with premier experts in cancer biology.
- Opportunities to develop expertise across chemical biology, structural, cellular and molecular biology, proteomics, and drug discovery.
- Opportunities for scientific growth, publication, grant writing, collaboration, and career development.
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Education Level
Ph.D. or professional degree
