The postdoctoral research associate position will conduct research in cellular and molecular biology in the Singh laboratory at Department of Molecular and Cellular Medicine, Texas A&M University Health Science Center. The laboratory applies and develops computational, and molecular biology approaches to understand regulation of gene expression in normal cells and disease states. The position will work on the project: Role of Intronic polyadenylation (IPA) isoforms across multiple cancer types. We have discovered that protein-coding genes can generate mRNAs that end in introns instead of annotated 3'UTRs. Our work showed widespread usage of intronic polyadenylation (IPA) sites across multiple cell-types and tissues generating IPA isoforms that diversify the transcriptome (Singh et al, Nature Communications 2018). This work established that these IPA isoforms represent major mRNA isoforms generated from alternative mRNA processing.
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Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree