Postdoctoral Research Associate - Hematology

St. Jude Children's Research Hospital • Memphis, TN

29d • $72,500 • Onsite

About The Position

A postdoctoral research associate position is available in the Yamashita lab. Project Description: Hematopoietic stem cells (HSCs) sustain lifelong blood production, and defects in their regulation contribute to diverse hematologic disorders, including clonal hematopoiesis, hematologic malignancies, and aplastic anemia. This project aims to define how T cell–mediated immune surveillance regulates HSC fate in the bone marrow and influences disease outcomes, ranging from immune tolerance and clonal expansion to graft-versus-leukemia activity and bone marrow failure. Using state-of-the-art mouse models, immunologic approaches, and single-cell technologies, the successful candidate will investigate the cellular and molecular mechanisms that govern immune–stem cell interactions. These studies will provide fundamental insights into hematopoietic homeostasis and uncover new therapeutic opportunities for hematologic disease.

Requirements

• PhD, MD, or MD/PhD. in Immunology, Hematology, Stem Cell Biology, Molecular Biology, Genetics, or a related field.
• Demonstrated research productivity and the ability to conduct independent scientific research.
• Strong background in immunology, hematology, stem cell biology, or a related biomedical discipline.
• Experience with mouse handling and in vivo experimentation.
• Experience with flow cytometry and immune cell phenotyping.
• Experience with standard molecular and cellular biology techniques.
• Ability to design and execute experiments, analyze data, and interpret results independently.
• Excellent written and oral communication skills, including scientific presentation and manuscript preparation.
• Strong organizational skills and the ability to work effectively both independently and as part of a collaborative team.
• Demonstrated commitment to scientific rigor, creativity, and problem-solving.

Nice To Haves

• Experience in T cell biology, hematopoiesis, stem cell biology, or bone marrow microenvironment.
• Experience with genomic, single-cell, or other high-dimensional data analyses.
• Familiarity with CRISPR-based genome engineering, transplantation models, or advanced immunological techniques.
• Experience with vaccine development, immunotherapy, or translational immunology.
• Interest in translational research related to hematologic disorders.

Responsibilities

• Conduct independent research on T cell–mediated regulation of hematopoietic stem cells and bone marrow immunity.
• Design and perform experiments using mouse models, flow cytometry, molecular biology, and immunological approaches.
• Apply single-cell and other advanced technologies to investigate immune–stem cell interactions and hematologic disease mechanisms.
• Analyze and interpret data, present findings at scientific meetings, and publish results in peer-reviewed journals.
• Collaborate with multidisciplinary teams and contribute to grant and manuscript preparation.
• Mentor students and trainees in a collaborative research environment.

Benefits

• Competitive salary starting at $72,500 a year
• Comprehensive benefits
• Generous relocation assistance
• Access to shared resources and facilities led by expert scientists
• Cutting-edge technology
• Customized professional and career growth programs
• Grant writing workshops
• Individual development plans
• Teaching and mentoring opportunities
• Non-research career advancement programs
• Professional development allowance

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree