Postdoctoral Research Associate - Chemical Biology and Therapeutics - Cupido Lab

St. Jude Children's Research HospitalMemphis, TN
Onsite

About The Position

The lab of Dr. Tommaso Cupido at St. Jude Children’s Research Hospital is seeking motivated, biology-inclined synthetic chemists to advance RNA proximity-induced pharmacology. This project focuses on the discovery, design, and development of small-molecule modulators using novel screening and compound optimization platforms. The research will target undrugged pathways and biological mechanisms regulating RNA biology and gene expression in cancer. The work will be conducted within the Department of Chemical Biology and Therapeutics at St. Jude Children’s Research Hospital, leveraging significant investments in high-throughput chemical discovery and synthesis infrastructure.

Requirements

  • Ph.D. in chemistry, chemical biology, or related fields.
  • Familiarity with multistep organic synthesis.
  • At least one first-author peer-reviewed publication (accepted or close to submission).

Responsibilities

  • Discovery, design, and development of small-molecule modulators.
  • Utilizing novel screening and compound optimization platforms.
  • Investigating biological mechanisms that regulate RNA biology and gene expression in cancer.
  • Conducting research within a world-class infrastructure for high-throughput chemical discovery and synthesis.

Benefits

  • State-of-the-art, fully staffed facilities for chemistry, biophysics, biochemistry, structural biology, mass spectrometry, genomics, cell microscopy and data-driven discoveries.
  • Highly collaborative and supportive research environment with premier experts in cancer biology.
  • Opportunities to develop expertise across chemical biology, structural, cellular and molecular biology, proteomics, and drug discovery.
  • Strong opportunities for scientific growth, publication, grant writing, collaboration, and career development.

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What This Job Offers

Job Type

Full-time

Career Level

Entry Level

Education Level

Ph.D. or professional degree

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