Postdoctoral Fellow - Hyun Jung Kim Lab
About The Position
Highly motivated individuals with a PhD or MD/PhD in a relevant area are encouraged to apply. This training position, under the direct supervision of a Cleveland Clinic Principal Investigator, will provide practical training and experience in a research setting. This position is appointed through Cleveland Clinic Research. The successful applicant will be able to demonstrate a commitment to research, a collaborative work ethic, and strong communication skills, both written and verbal. This program is expected to be completed within 5 years. Compensation follows the NIH NRSA Postdoctoral Salary Scale based on total years of postdoctoral experience.
Requirements
- PhD or MD/PhD required
- English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status
- Previous experience in a research or academic setting. Graduate student experience meets this requirement.
- Scientific writing experience
- Ability to perform work in a stationary position for extended periods
- Ability to operate a computer and other office equipment
- Ability to communicate and exchange accurate information
- Ability to distinguish color
- Manual dexterity to handle specimens and repair equipment
- Ability to lift and transport equipment or specimens weighing up to 20 pounds
- May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.
Nice To Haves
- Expertise in microbial biochemistry and enzymology
- Expertise in glycobiology and carbohydrate-active enzymes (CAZymes)
- Expertise in proteomics-based target identification
- Expertise in protein engineering
- Expertise in microbial synthetic biology
- Experiences in engineering designer probiotics or liver biotherapeutics for targeted payload delivery or tumor-localized sensing
- Candidates trained in host-microbiome biochemical interactions, glycoprotein processing, microbial physiology, or AI-assisted synthetic biology are especially encouraged to apply.
- Expertise in organoid and 3D cell culture
- Expertise in host-microbiome crosstalk and mucosal immunology
- Expertise in cellular and molecular phenotyping
- Expertise in mechanobiology and biophysical processes
- Expertise in GI disease pathology
- Hands-on experience in organ-on-a-chip, microphysiological systems (MPS), or new approach methodologies (NAM)
- A strong foundation in traditional biochemistry or cell biology, combined with enthusiasm for emerging microphysiological platforms, is equally welcome.
Responsibilities
- Investigate how gut microbes modulate immune checkpoints on colorectal cancer (CRC) cells.
- Identify responsible microbial enzymes and elucidate their mechanism of action.
- Investigate how the gut microbiome drives human GI diseases using next-generation organoid and organ-on-a-chip platforms.
- Elucidate microbiome-driven mechanisms underlying inflammatory bowel disease (Crohn's disease and ulcerative colitis), intestinal fibrosis, CRC, celiac disease, and GI infectious diseases, advancing precision therapeutics and translational medicine.
Benefits
- Compensation follows the NIH NRSA Postdoctoral Salary Scale based on total years of postdoctoral experience.
- Outstanding, comprehensive offerings are an investment in your health, well-being and future.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
