Postdoctoral Associate

Stony Brook University • Town of Brookhaven, NY

3d • Onsite

About The Position

The Postdoctoral Associate will assist the Principal Investigator Dr. Raymond Bergan in the Department of Medicine. The incumbent will conduct research and ensure that all experiments are appropriately conducted following the policies and procedures of Stony Brook University.

Requirements

• Doctoral Degree (PhD) or foreign equivalent in Cancer Biology, Molecular and Cellular Biology, Biochemistry, or a closely related field.
• Research Laboratory skills that include, but not limited to PCR, generation of stable lentiviral cell lines, western blotting, immunofluorescence staining and confocal microscopy; cell proliferation and migration assays, including Boyden chamber and wound-healing/scratch assays and In Vivo mouse techniques, including handling and restraint, oral gavage and subcutaneous intraperitoneal and intravenous (tail-vein) injections.

Nice To Haves

• Research Lab experience in cancer cell biology and cell motility/migration in prostate cancer models.
• Hands-on experience in mammalian cell culture, molecular cloning (Gibson, In-Fusion, and restriction enzyme cloning), primer and construct design in SnapGene, site-directed mutagenesis, and molecular knockout.
• Experience in mass spectrometry-based proteomics, including data deposition and retrieval through the PRIDE (Proteomics Identifications) database, and in bioinformatic data analysis, including pathway and ontology enrichment (ORA and GSEA) using clusterProfiler, WebGestalt, g:Profiler, Enrichr, or QIAGEN Ingenuity Pathway Analysis (IPA); protein–protein interaction and functional network analysis using the STRING database and Cytoscape; and structural contextualization by mapping peptides and PTM sites onto 3D protein structures from the Protein Data Bank (PDB), AlphaFold DB, or UCSF ChimeraX.
• Proficiency in statistical analysis and data visualization using GraphPad Prism.
• Experience with scientific writing, peer reviewed publications and conference presentations.

Responsibilities

• Conduct research experiments in the field of cancer cell biology and cell motility, including in vitro and in vivo (mouse model) studies of prostate cancer cell migration and its therapeutic modulation by selective chemical probes.
• Collect and analyze data, including periodical/literature search and utilizing specialized skills in related field, such as mass spectrometry-based proteomics, functional enrichment and network analysis, and structural bioinformatics, to analyze the collected data.
• Participate/assist in manuscript writing for publication in scientific journals and/or presentations. May also assist in grant writing.
• Lab maintenance, including equipment maintenance and ordering of supplies as needed.
• Other duties as assigned, which may include attending Scientific Conferences and Meetings.

Benefits

• The Research Foundation of SUNY policies and procedures
• Sponsor guidelines
• Availability of funding
• FLSA Exempt position, not eligible for the overtime provisions of the FLSA.
• Minimum salary threshold must be met to maintain FLSA exemption.
• Access to The Office of Postdoctoral Affairs to learn more about our postdoctoral community.
• Consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, familial status, sexual orientation, gender identity or expression, age, disability, genetic information, veteran status and all other protected classes under federal or state laws.
• Disability-related accommodation services.
• Total rewards offered by SBU.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree