POSTDOCTORAL ASSOCIATE - BRENNER LAB
About The Position
Sanford Burnham Prebys is much more than a research facility and hub for innovation; it’s a vibrant global community of talented scientists and researchers from over 30 countries. This worldwide representation enriches our perspectives and enhances our creative approach to solving complex scientific challenges. We strive to be leaders not only in biomedical research but also in creating an environment where excellence thrives through collaboration across cultures and backgrounds. Our mission is to advance the biomedical sciences by cultivating the next generation of scientific leaders, providing meaningful opportunities for researchers of all backgrounds to learn, innovate, and make breakthrough discoveries that improve human health. Together, we translate science into health. The duties and responsibilities contained in the job description are intended to be examples of the accountabilities for which the person in the position will demonstrate competency through performance. The job description is not intended to be an all-inclusive list. Duties and responsibilities are subject to change and other duties may be assigned as necessary. Position Summary: Research in the Brenner lab (https://sbpdiscovery.org/scientists/david-a-brenner-md/ [https://sbpdiscovery.org/scientists/david-a-brenner-md/]) studies a wide variety of liver diseases, such as liver fibrosis, HCC and Metabolic dysfunction associated steatohepatitis (MASH) and Alcohol associated liver disease (ALD). Using both in vivo mouse models as well as primary human cells, the overarching goal of the lab is to understand the cell-cell interaction and the basic mechanisms of disease development in order to identify novel therapeutic approaches. A Postdoctoral Associate position is available to study: The mechanism of liver fibrosis and liver cancer development. Understand the mechanism of activation of hepatic stellate cells in MASH. Under limited direction, the Postdoctoral Associate will plan and manage all aspects of a research project including research design, experimentation, funding acquisition and publication.
Requirements
- Ph.D. in biomedical sciences
- Experience with mammalian cell culture, molecular biology techniques, lentiviral production, overexpression and knock-down or knock-out genes in vitro
- Expertise in mouse handling and in vivo techniques such as i.v., IP, oral gavage, sub-cutaneous injection is required
- Experience in harvesting and processing various mouse tissues in required.
- Experience with immunohistochemistry and microscopy is required
- Demonstrated ability to conduct and publish research projects
- Work independently as well as in a team environment
- Be responsible and have strong time management skills
- Able to analyze and resolve issues of high/moderate complexity
- Possess strong attention to detail and organizational skills
- Demonstrate professional communication and interpersonal skills
- Professional proficiency in Microsoft Office, Adobe Photoshop/Illustrator, Prism, ImageJ
- Embody the Institute’s core values of Commitment, Collaboration, Communication, Community and Compassion
Nice To Haves
- Isolation of various primary cell types from the liver in preferable
- Ability to perform basic bioinformatics analysis of bulk or single cell RNAseq data is preferable.
Responsibilities
- Research design and planning
- Experimentation and trouble-shooting
- Data collection, analysis and interpretation
- Data recording and compliance
- Management of collaborations
- Results summarization
- Preparation of grants and manuscripts
Benefits
- reasonable accommodations for the hiring process
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
