Post-Doctoral Scientist - Formulations Bioproduct Research & Development - FDE

Eli Lilly and Company • Us, IN

3d • Onsite

About The Position

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. When it comes to research and development, our goal is to discover and deliver innovative medicines that make life better for people around the world. It’s challenging, expensive and often unpredictable. Yet each outcome advances medical science and deepens our understanding of disease, biology and chemistry – ultimately bringing new solutions one step closer to reality. Over the course of our history, we have shed light on some of the toughest health care problems known to humankind – diabetes, heart disease, infectious diseases, neuroscience disorders, cancer and more. We could not pursue this without our research and development team. Postdoctoral scientists help us continue this pursuit. During your experience you will get: Top industry research experience Mentoring by some of Lilly’s top scientists Laboratory and technical training and pharmaceutical science education to further your development Collaboration and networking across dozens of postdoctoral scientists and other researchers We are seeking an ambitious post-doctoral scientist, with strong research and communication skills, in advancing innovative protein and peptide therapeutics. This role focuses on translating mechanistic insights at the molecular level into robust platform formulation strategies that enable the next generation of biological drug products.

Requirements

• Ph.D. in relevant fields such as Biophysics, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, Biomedical Engineering, or closely related discipline.
• Strong foundation in protein biophysics, structural biology, biologic formulation science, or analytical characterization of peptide/protein therapeutics.
• Qualified applicants must be authorized to work in the United States on a full-time basis.

Nice To Haves

• Hands-on experience with structural and biophysical techniques such as Bio-NMR, SAXS (Small Angle X-ray Scattering), neutron scattering, X-ray crystallography, Cryo-EM, SEC-MALS, SLS/DLS, DSC, ITC, mass photometry, HDX-MS, HPLC/UPLC, XRPD, or related methods.
• Experience with crystallization screening, solid-state characterization, or excipient-binding analysis.
• Familiarity with PK/PD concepts, translational pharmacology, or approaches that link in vitro molecular behavior to in vivo performance.
• Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.
• Excellent communicator (oral and written) with presentation experience, along with a strong publication record.
• Proficiency in data analysis and scientific reporting.

Responsibilities

• Investigate the physical stability of various modalities under different formulation parameters such as pH, concentration, ionic strength, and more.
• Apply a range of biophysical and analytical techniques to characterize molecular interactions within formulations and assess their impact on higher-order structure, viscosity, rheology, and overall stability.
• Develop mechanistic or kinetic models linking formulation and PK/PD-relevant outcomes.
• Stay abreast of current scientific literature and critically evaluate published findings to inform and guide experimental design.
• Collaborate closely with cross-functional teams across drug substance, drug product, structural biology, analytical sciences, biophysical characterization, formulation, computational modeling, and translational pharmacology.
• Identify areas of key need across drug product development and champion creative solutions to address those needs.
• Present findings at conferences and publish in high-quality peer-reviewed journals.
• Prepare technical reports, research summaries, peer-reviewed manuscripts, conference presentations, and invention disclosures as appropriate.
• Maintain awareness of emerging technologies in structural biology, protein biophysics, drug delivery, and pharmaceutical development.

Benefits

• Eligibility to participate in a company-sponsored 401(k)
• Pension
• Vacation benefits
• Eligibility for medical, dental, vision and prescription drug benefits
• Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
• Life insurance and death benefits
• Certain time off and leave of absence benefits
• Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

What This Job Offers

• Career Level: Entry Level
• Education Level: Ph.D. or professional degree