Post-Doctoral Research Fellow

Fred Hutchinson Cancer Center • Seattle, WA

7d • Onsite

About The Position

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington. With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality. At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. The Boonyaratanakornkit Laboratory within the Vaccine and Infectious Disease Division is recruiting a Post-Doctoral Research Fellow with experience in virology, molecular biology, and/or immunology. The lab studies respiratory and herpes viruses that afflict vulnerable patients who are at heightened risk for serious complications or death. We study the humoral immune system (B cells and antibodies) using highly sensitive techniques to identify protective responses against viruses. We leverage this information to develop immune-based therapies. Current projects in the lab are aimed at studying rare B cells targeting common viruses, like respiratory syncytial virus, human metapneumovirus, parainfluenza viruses, coronaviruses, rhinoviruses, and cytomegalovirus. The lab is also engineering antibodies to enhance their ability to prevent and treat viral infections in vulnerable patients. Our lab is seeking post-doctoral fellows who are interested on studying humoral immune responses to viral infections and developing drugs that protect against viral infections. We strive to provide a creative, collaborative, fun, and exciting research and training environment. Check out our lab website for more information: https://research.fredhutch.org/boonyaratanakornkit/en.html Applications should include a CV, the names of 2-3 references, and a short cover letter describing their research interests.

Requirements

• A doctoral degree (PhD, MD, or equivalent) in molecular biology, cellular biology, virology, immunology, microbiology, or a similar area of focus
• An interest in B cell immunology, antibodies, biochemistry, and/or viruses
• Experience in cloning and cell culture
• Willingness to work with biohazardous/infectious agents (BSL-2 +/- BSL-3), human specimens, and rodent colonies under carefully controlled conditions
• Excellent attention to detail and the ability to work independently
• Ability to learn new techniques and troubleshoot assays
• Good communication, organizational, and record-keeping skills
• Flexibility and willingness to work some evenings and weekends as needed

Nice To Haves

• Experience in flow cytometry, virology, reverse genetics, and/or next-generation sequencing
• Experience with protein expression and purification, structural biology, and/or protein design

Responsibilities

• Perform standard laboratory techniques, such as PCR, cell culture, ELISA, cloning, Sanger sequencing, and flow cytometry
• Design oligonucleotides and perform quantitative PCR (real-time or digital) and next-generation sequencing
• Produce and purify proteins, viruses, and virus-like particles
• Perform high throughput neutralization assays
• Work with preclinical small animal models of viral infection
• Collect, analyze, interpret, and record experimental data
• Design, plan, coordinate, initiate, and implement scientific projects with Dr. Boonyaratanakornkit and collaborators
• Develop new protocols and new ideas for projects or approaches based on research interests and knowledge of the literature
• Identify methodological problems in research protocols and implement modifications to optimize experimental results
• Present data at meetings/seminars and prepare manuscripts for publication

Benefits

• medical/vision
• dental
• flexible spending accounts
• life
• disability
• retirement
• family life support
• employee assistance program
• onsite health clinic
• income-based child care subsidy
• tuition reimbursement
• paid vacation (22 days per year)
• paid sick leave (up to 30 calendar days per occurrence of a qualifying reason)
• paid holidays (13 days per year)
• paid parental leave (up to 4 weeks)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree