Post-Doctoral Fellow

University of Colorado • Aurora, CO

6d • $63,480 - $70,500 • Onsite

About The Position

We are searching for a qualified post-doctoral fellow to join our growing laboratory, whose principal investigator in a physician scientist. The post-doctoral fellow would conduct research focused on the immune mechanism of cholestatic liver disease, particularly the role of macrophages and how polyamines can regulate macrophage function. The expected focus of experiments will include but is not limited to: 1) in vivo experiments (mice) and in vitro (mice and human) experiments testing the ability for polyamines to promote anti-inflammatory macrophage polarization; 2) in vivo and in vitro assays testing the impact of polyamines on macrophage phagocytosis and efferocytosis activity; 3) in vivo experiments testing therapeutic efficacy of polyamines; and 4) transcriptomic analyses (scRNA-seq and spatial) across experiments. The post-doctoral fellow will be supported by an already funded R01. Successful applicants will be expected to demonstrate a strong work ethic, good team communication skills, independent experimental planning, strong scientific writing, and detail-oriented technical and record-keeping skills.

Requirements

• PhD in relevant scientific area such as Cell Biology, Molecular Biology, Immunology
• Experience with fundamental technical skills including immunohistochemistry, immunofluorescence, western blot, real-time PCR, and data analysis
• Ability to work independently as well as collaboratively
• Strong organizational skills and attention to detail
• Strong communication skills and ability to work in a team
• Detailed record keeping of experiments
• Knowledge of basic statistics and analysis tools

Nice To Haves

• Experience in flow cytometry sample preparation, data acquisition, and analysis
• Experience in coding and basic transcriptional analyses
• Prior cell culture experience
• Experience in mouse models

Responsibilities

• Independently design and perform rigorous scientific experiments
• Develop and validate new laboratory techniques
• Perform transcriptomic data analysis
• Present research at national and internation meetings
• Write and submit high impact scientific manuscripts
• Develop grant-writing skills with potential application for small grants
• Teach and mentor rotating students, clinical residents/fellows
• Teach/supervise professional research associates

Benefits

• Comprehensive benefits package
• Generous leave
• Health plans
• Retirement contributions

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree