Post Doctoral Fellow for Research Lab

Saint Louis University • St. Louis, MO

7d • Onsite

About The Position

A postdoctoral fellow research position is available, focused on pediatric intestinal failure, short bowel syndrome, parenteral nutrition associated injury, bile acid signaling, microbiome related mechanisms, epithelial biology, liver injury and other systemic processes and diseases. The successful candidate will join a multidisciplinary team studying how intestinal nutrient exposure, microbial metabolites, epithelial signaling, and gut and liver communication regulate intestinal adaptation, barrier function, inflammation, liver disease and other systemic processes and diseases. The postdoctoral fellow will work across complementary experimental systems, including neonatal large animal models, intestinal epithelial organoid-derived cultures, liver organoid or liver-derived cell systems, human tissue-based studies, molecular and multi-omic assays and others.

Requirements

• PhD, MD, MD/PhD, DVM, or equivalent doctoral degree in a relevant field, including biology, physiology, molecular biology, microbiology, immunology, pathology, biomedical sciences, nutrition, or related disciplines.
• Highly motivated, organized, detail-oriented.
• Able to work both independently and collaboratively.
• Strong written and oral communication skills.

Nice To Haves

• Experience with cell culture, organoid systems, molecular biology, animal models, gastrointestinal biology, liver biology, microbiome research, immunology, histology, transcriptomics, metabolomics, or bioinformatics.
• Prior experience with large animal models.
• Interest in translational pediatric gastrointestinal and liver research, intestinal failure, epithelial biology, bile acid signaling, host-microbe interactions, inflammation, or organ crosstalk.

Responsibilities

• Participate in experimental planning, execution, data analysis, and interpretation.
• Large animal sample collection and processing.
• Epithelial organoid culture and functional assays.
• Liver organoid or liver-derived cell assays.
• Molecular biology, immunostaining, imaging, quantitative PCR, ELISA or multiplex assays.
• Microbiome and metabolomic sample preparation.
• Bile acid and short chain fatty acid related analyses.
• Integration of physiologic, histologic, molecular, omics datasets and tasks as required by the lab.
• Maintain accurate laboratory records.
• Contribute to protocol development and quality control.
• Prepare figures and manuscripts.
• Present findings at laboratory meetings and scientific conferences.
• Assist with grant progress reports and future grant applications.
• Close collaboration with investigators in pediatric gastroenterology, hepatology, pathology, microbiology, immunology, surgery, veterinary medicine, bioinformatics, core facilities, other departments, individuals and labs.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree