Wayne State University is searching for an experienced Post Doctoral Fellow - Department of Pharmaceutical Sciences at its Detroit campus location. Wayne State is a premier, public, urban research university located in the heart of Detroit, Michigan where students from all backgrounds are offered a rich, high-quality education. Our deep-rooted commitment to excellence, collaboration, integrity, diversity and inclusion creates exceptional educational opportunities which prepare students for success in a global society. The purpose of the Postdoctoral Scholar/Fellow positions is to provide individuals, who have recently (within the past 6 years) completed a doctoral degree, with a full-time program of advanced academic preparation and research training under the guidance of a supervising Faculty Mentor. Postdoctoral appointments are temporary by nature and are designed to develop the Postdoctoral Scholar/Fellow as an independent scientist and to enhance their professional skills. Postdoctoral Scholars/Fellows are considered to be in training for future faculty teaching/ research positions or for a position suited to their desired career outcomes and recognized for their dual status as trainees and employees. Postdoctoral Scholars/Fellows provide leadership in the design and management of research programs. They additionally assist their Faculty Mentor(s) in designing protocols as well as training and/or supervising technical research staff to complete research projects. With the assistance of the Faculty Mentor, postdoctoral scholars/fellows write research grants with the goal of obtaining additional research grants. They conduct independent research that is expected to result in scholarly publications and presentations for research funding at scientific meetings. The postdoctoral scholars/fellows complete technical laboratory and/or field experimental procedures. They conduct independent research with grant funding they were responsible for obtaining. Postdoctoral scholars /fellows, with permission and supervision of their mentor(s), may also be involved with the training of undergraduate and graduate students in the laboratory, which is another key aspect towards their preparation for future academic and non-academic positions. Determine roles for oxidative stress-related signaling steps in the onset of nuclear oxidative stress leading to beta cell death under diabetogenic conditions. Conduct proteomic studies for the identification of interaction partners of specific small G proteins (e.g., Rac1) and its corresponding signaling pathways in islet beta cells exposed to metabolic stress. Evaluate novel small molecule inhibitors of Rac1 in alleviating intracellular oxidative stress and beta-cell dysfunction in the diet-induced obesity animal model.
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Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree