DEL Platform Scientist I

WuXi AppTecNatick, MA
Onsite

About The Position

DNA‑encoded library (DEL) and SELEX (Systematic Evolution of Ligands by EXponential enrichment) technologies are rapidly expanding drug discovery platforms within the IVBU at WuXi AppTec. These multidisciplinary platforms integrate chemistry, chemical biology, molecular biology, and informatics to enable the discovery of novel binders and lead compounds. We are seeking a motivated and technically strong Scientist I to join our DEL/SELEX screening team. The successful candidate will work closely with senior scientists and cross‑functional teams to execute high‑quality DEL and SELEX screening projects, analyze data, and support timely delivery of results to internal teams and external clients.

Requirements

  • 1–3 years of relevant experience in DEL, SELEX, or related affinity-based selection technologies
  • 1–3 years of relevant industry experience, or a combination of industry and advanced academic research experience, in DEL, SELEX, or related affinity-based selection technologies.
  • Demonstrated hands on experience in several of the following areas: Affinity based selection technologies (e.g., DEL, SELEX, mRNA display), Molecular biology techniques (e.g., molecular cloning, PCR, qPCR, gel electrophoresis), Flow cytometry and FACS sorting, Recombinant protein expression, purification, and handling, In vitro assay development (biochemical and/or biophysical)
  • Experience analyzing experimental data and summarizing results for internal stakeholders.
  • Ability to work effectively in collaborative, multidisciplinary teams.
  • Strong technical foundation in molecular biology and/or chemical biology techniques relevant to DEL and SELEX screening.
  • Ability to work independently on assigned tasks while seeking guidance when appropriate.
  • Proficiency in literature review and applying scientific findings to experimental design.
  • Ability to manage multiple tasks and prioritize work in a fast‑paced environment.
  • Strong scientific communication skills, including data presentation and technical writing.
  • Flexibility to adjust workload as needed to meet project timelines.

Responsibilities

  • Execute DEL and/or SELEX screening experiments, including sample processing and downstream analysis, under the guidance of senior scientists or project leads.
  • Support assigned DEL/SELEX projects by contributing to experimental planning, execution, troubleshooting, and documentation.
  • Analyze screening data and assist in the preparation of technical reports and project summaries.
  • Participate in internal technical discussions and project meetings; support client communications as needed.
  • Contribute to internal DEL/SELEX research and development activities aimed at improving screening workflows and platform performance.
  • Maintain accurate experimental records and ensure compliance with company standards and safety guidelines.
  • Perform additional duties as assigned.
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