Pharmacology Senior Research Associate

Vertex Inc.•Boston, MA

5d•$76,100 - $114,100•Onsite

About The Position

The Pharmacology Senior Research Associate conducts independent research to evaluate the effects of compounds on in vivo disease biology, with a strong emphasis on in vivo pharmacology and surgical execution in rodent models. This role requires excellent technical skills, strong attention to detail, and the ability to troubleshoot and adapt experimental approaches. The ideal candidate will have hands-on experience with rodent surgical procedures, including kidney-related surgeries such as renal pelvis injection, and a strong understanding of kidney anatomy. Large animal in vivo surgical experience is a plus. This individual should demonstrate strong in vivo technical expertise, scientific rigor, and the ability to generate high-quality data in a collaborative research environment. In addition to technical strength, the successful candidate will bring a strong team-oriented mindset, a positive, can-do attitude, and a willingness to support team and project goals.

Requirements

Strong hands-on experience in in vivo pharmacology, with demonstrated success in rodent studies
Proven technical expertise in rodent surgical procedures, particularly kidney surgery, including renal pelvis injection
Strong understanding of kidney anatomy and its application to experimental design, surgical procedures, and tissue evaluation
Experience with a broad range of in vivo techniques, including animal handling, dosing via multiple ROAs, perfusion, fluid collection, and tissue dissection/processing
Strong analytical and problem-solving abilities, including data interpretation and protocol refinement
Consistent reliability in experimental execution, data quality, and study delivery
Effective written and verbal communication skills
Strong teamwork spirit, a collaborative mindset, and a can-do attitude
Bachelor’s degree in a biological science required
Typically requires: Bachelor’s degree with 4+ years of experience, or Master’s degree with 0–2 years of experience, or equivalent combination of education and experience

Nice To Haves

Large animal in vivo and/or surgical experience is a plus
Developing knowledge of related scientific disciplines

Responsibilities

Execute and interpret in vivo experiments with a high level of reliability, independence, and scientific rigor
Perform and support in vivo pharmacology studies, primarily in rodent models
Conduct rodent surgical procedures with strong technical proficiency, including kidney surgeries such as renal pelvis injection
Apply knowledge of kidney anatomy to support study planning, surgical execution, tissue collection, and data interpretation
Perform core in vivo procedures, including: Animal handling, Dosing via multiple routes of administration (ROAs), Blood and other fluid sample collection, Perfusion, necropsy, tissue dissection, and tissue processing
Contribute to experimental planning and support prioritization of studies based on project impact
Perform basic statistical analyses, as appropriate
Routinely troubleshoot experiments and refine methods to improve study outcomes
Prepare clear protocols, surgical procedures, and written study reports
Maintain awareness of relevant scientific literature, technical advances, and disease area trends
Present study results clearly and effectively at internal meetings
Work collaboratively across teams and contribute positively to a highly interactive research environment
Perform additional duties as assigned