Pharmaceutical Scientist (R2-R4)
About The Position
Eli Lilly and Company seeks a Pharmaceutical Scientist (R2-R4) to develop nucleic acid-based formulations for therapeutic candidates. This role involves designing, implementing, and troubleshooting laboratory experiments for lipid nanoparticle (LNP) formulations from small scale to mid-scale. The scientist will perform daily characterization of LNPs, assessing stability using particle sizing, Ribogreen assay, and osmometry. Key responsibilities include optimizing current formulation methods and processes for the delivery of nucleic acids, screening optimal processes for mid-scale production to support large animal studies, and developing comprehensive standard operating procedures (SOPs) and generating test method documentation. The role also requires interpreting and analyzing data, maintaining comprehensive records of multiple laboratory projects, and supporting downstream processing of nucleic acid-based formulations.
Requirements
- Master’s degree in Chemistry, Pharmaceutical Science, or a related scientific field.
- 1 year of experience with researching nucleic acid formulation and characterization or 1 year of experience with polymeric nanoparticles formulation and characterization.
- Minimum of 1 year of experience with analytical techniques for characterizing nanoparticles, including Dynamic Light scattering, Zeta potential, and Ribogreen.
- Minimum of 1 year of experience with preparation of nanoparticle-based formulations at scales sufficient to support in vitro and in vivo studies.
- Minimum of 1 year of experience with wet lab biology techniques.
- Minimum of 1 year of experience with designing formulation methods, composition, and process parameters.
Responsibilities
- Design, implement, and troubleshoot laboratory experiments for lipid nanoparticle (LNP) formulations from small scale to mid-scale.
- Perform daily characterization of LNPs, assessing stability using particle sizing, Ribogreen assay, and osmometry.
- Optimize current formulation methods and processes for delivery of nucleic acids.
- Screen optimal process to enable midscale production which supports large animal studies.
- Develop comprehensive standard operating procedures (SOPs) and generate test method documentation.
- Interpret and analyze data and maintain comprehensive records of multiple laboratory projects.
- Support downstream processing of nucleic acid-based formulations.
Benefits
- company bonus
- company-sponsored 401(k)
- pension
- vacation benefits
- medical benefits
- dental benefits
- vision benefits
- prescription drug benefits
- flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
- life insurance
- death benefits
- certain time off and leave of absence benefits
- well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
