Pathology Sr. Director

AmgenThousand Oaks, CA

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Requirements

  • DVM and 7 years of pathology or toxicology experience OR Master’s degree and 10 years of pathology or toxicology experience OR Bachelor’s degree and 12 years of pathology or toxicology experience

Nice To Haves

  • DVM, Board Certification in Veterinary Anatomic Pathology (DACVP or comparable credentialing body) and PhD in pathology or toxicology.
  • At least 15 years’ experience in the pharmaceutical sector as a discovery and toxicologic pathologist and an additional 5 years’ experience integrating pathology data into bioinformatics efforts in a pharmaceutical environment.
  • Experience in pathology data management within pharmaceutical environments is highly desirable.
  • Demonstrated experience working with large-scale imaging datasets (e.g., whole-slide images) and associated metadata in distributed or cloud environments and analysis outputs.
  • Experience with annotation platforms, digital pathology pipelines, or whole-slide image analysis environments.
  • Familiarity with IHC assay workflows and digital slide scanning.
  • Experience in interpretating dearly target discovery pathology and toxicology studies.
  • Strong problem-solving skills and solution-oriented mindset, particularly when diagnosing and resolving data quality or workflow issues.

Responsibilities

  • Ensure incoming datasets are delivered according to defined data formats, metadata standards, and project requirements.
  • Translate scientific and model development requirements into structured dataset preparation tasks with pathology scientists and pathologists.
  • Ensure imaging data, annotations, and metadata are suitable for downstream AI/ML model development, validation, and scientific analysis.
  • Execute computational pathology workflows across AI model development and discovery projects for image analysis workflows to generate quantitative readouts supporting discovery and program decision-making within cloud-based data platforms (e.g., Deciphex Patholytics, Procia-Concentriq).
  • Identify opportunities to improve data workflows, tooling, and operational processes within computational pathology.
  • Stay informed about emerging data management practices, digital pathology technologies, and AI data standards.
  • Provide pathology expertise to the design and conduct of GLP and non-GLP nonclinical safety studies to enable progression of discovery and development programs to decision points inclusive of pathology peer reviews and report review of integrated toxicology reports for finalization.
  • Serve as a contributing author to pathology sections of regulatory documents such as INDs, NDA/BLAs, IBs, and respond to Health Authority questions.

Benefits

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible.
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