On-Demand Bioinformatician – Viral Genomics & Diagnostics

Primary.Health•San Francisco, CA
•$85 - $100•Remote

About The Position

Primary.Health is seeking an experienced bioinformatician for a part-time retainer to analyze viral sequence data, track emerging variants, and advise on how genomic changes may affect diagnostic tests. The position is remote, with flexible scheduling and occasional faster turnaround needs during outbreaks or the emergence of new variants. The retainer is 10 hours per week, with additional hours billed at the agreed hourly rate.

Requirements

  • Advanced degree in Bioinformatics, Computational Biology, or a related field, or equivalent experience.
  • At least 3 years of hands-on viral or pathogen genomics experience.
  • Proficiency in Python and/or R and standard genomics tools.

Nice To Haves

  • Experience evaluating molecular diagnostics against sequence variation.
  • Familiarity with tools such as Nextclade, Pangolin, and Nextstrain.

Responsibilities

  • Analyze viral genomes, including SARS-CoV-2, influenza, and RSV, to identify mutations, lineages, and variants of concern.
  • Assess how sequence changes may affect assay performance, including primer and probe binding and sensitivity.
  • Run and maintain reproducible pipelines for alignment, variant calling, and lineage assignment.
  • Summarize findings clearly for non-technical stakeholders.
  • Monitor CDC, WHO, and GISAID surveillance and flag relevant developments.
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