Manufacturing Supervisor – Downstream Bioprocessing (Night Shift)

Elanco • Elwood, KS

4d • Onsite

About The Position

The Manufacturing Supervisor – Downstream Bioprocessing leads manufacturing personnel and daily operations supporting bulk production of monoclonal antibody (mAb) products at Elanco’s Elwood, Kansas manufacturing site. The role oversees downstream bioprocessing operations and ensures production targets are achieved while maintaining safety, quality, regulatory compliance, and Good Manufacturing Practices (cGMP). The supervisor also develops team members, drives operational excellence, and fosters accountability and continuous improvement.

This is an onsite night-shift role working 5 p.m. to 5 a.m. in a 12-hour, two-week rotation. The shift structure may change with notice according to business demands. Travel is minimal, at 0–5%. Night and weekend premiums are available: 10% for night weekdays and 14% for night weekends.

Requirements

• High school diploma or equivalent.
• At least 3 years of experience in a regulated, commercial manufacturing environment.
• Ability to wear appropriate gowning and personal protective equipment in manufacturing and support areas.

Nice To Haves

• Bachelor’s degree in a biomanufacturing-related field.
• Biomanufacturing experience.
• Monoclonal antibody manufacturing experience.
• Understanding of USDA, FDA, EU GMP, and cGMP regulatory standards.
• Experience with operational excellence, lean manufacturing, Six Sigma, or TPS.
• Demonstrated success in leadership.
• Experience with SAP, OSI PI, or VEEVA.

Responsibilities

• Lead and oversee daily downstream bioprocessing manufacturing operations, including buffer formulation, cell clarification, protein A chromatography, and Tangential Flow Filtration; partner with upstream and fill/finish teams and adhere to production schedules.
• Supervise, coach, and develop manufacturing personnel through performance management, training, and regular feedback.
• Ensure manufacturing activities comply with USDA, EMA, cGMP requirements, approved procedures, and batch production records.
• Maintain a production-floor presence to promote safe work practices, operational excellence, quality, and accountability.
• Coordinate with Quality, Engineering, Maintenance, Validation, Supply Chain, and other cross-functional teams to support compliant and efficient operations.
• Monitor production performance, equipment readiness, and schedule adherence; ensure timely completion of batch records, SAP transactions, and manufacturing documentation.
• Lead or support investigations, root cause analyses, and corrective and preventive actions (CAPA) for operational events, deviations, and equipment or process issues.
• Drive continuous improvement initiatives to enhance efficiency, strengthen compliance, and improve operational performance.

Benefits

• 8-week parental leave.
• 9 Employee Resource Groups.
• Annual bonus offering.
• Up to 6% 401(k) matching.
• Night and weekend shift premiums: 10% for night weekdays and 14% for night weekends.

What This Job Offers

• Job Type: Full-time
• Career Level: Manager
• Education Level: High school or GED