Manager, Manufacturing

Lonza•Portsmouth, NH

1d•Onsite

About The Position

The Manufacturing Manager provides leadership and oversight for Cell Therapy manufacturing operations, ensuring a safe, compliant, and efficient production environment. The role serves as a subject matter expert for assigned manufacturing areas and leads teams delivering clinical and commercial products. Based at the Portsmouth, New Hampshire facility, the position typically follows regular office hours, with flexibility to support critical manufacturing operations as required. Travel is expected to be less than 10%. The manager may serve as delegate for the Manufacturing Director during periods of absence.

Requirements

Experience leading manufacturing operations in biopharmaceutical, biologics, cell therapy, or related GMP-regulated environments.
Demonstrated leadership experience managing teams, organizational change, hiring, training, and employee development.
Experience supporting technical transfers, project execution, and commercialization of manufacturing processes.
Strong knowledge of cGMP requirements, quality systems, deviation management, and manufacturing compliance expectations.
Experience with biological manufacturing operations, including fermentation, purification, drug product filling, freezing operations, or related modalities.
Strong business acumen, customer focus, collaboration, and ability to drive results in a fast-paced manufacturing environment.
Excellent communication, stakeholder management, and cross-functional collaboration skills.
Proven ability to manage priorities, budgets, continuous improvement initiatives, and operational performance metrics.

Nice To Haves

Bachelor’s degree preferred; equivalent industry experience may be considered in lieu of a degree.
Experience with automated drug product filling systems utilizing RABS and/or isolator technology.
Experience with automated or manual visual inspection systems.

Responsibilities

Provide a safe, controlled work environment and communicate site safety objectives to manufacturing personnel.
Lead manufacturing teams and serve as the subject matter expert for assigned operations, including Cell Growth, Drug Product Filling, and related manufacturing processes.
Provide in-suite oversight during critical manufacturing activities, including harvest, vial filling, visual inspection, and other key production operations.
Support technical transfer activities, including process execution, methods transfer, engineering runs, training runs, water runs, and qualification activities.
Collaborate with Quality Assurance and cross-functional teams to establish procedures, quality systems, and manufacturing strategies for new and existing programs.
Partner with Internal Project Teams, Joint Project Teams, customers, and stakeholders to transfer and maintain processes in the manufacturing facility.
Manage manufacturing-related deviations, change controls, and lessons learned, and support continuous improvement initiatives.
Support hiring, development, training, and performance management of manufacturing staff while fostering a high-performing team culture.
Work with Manufacturing Technical Managers to identify equipment, material, and resource requirements for production operations.
Partner with leadership on financial reporting, project progression, proposal support, and operational execution across Cell Therapy programs.
May serve as delegate for the Manufacturing Director during periods of absence.