Manager, Promotional Review and Operations

AstraZeneca • Boston, MA

2d • $115,000 - $173,000

About The Position

AstraZeneca is seeking a Manager, PRC Coordinator, Promotional Review & Operations (PRO) to lead end-to-end performance of the promotional review portfolio across assigned therapeutic areas and business priorities. The role integrates portfolio planning, submission readiness, workflow orchestration, launch execution, stakeholder alignment, lifecycle management, performance monitoring, and continuous improvement while maintaining compliance with applicable policies, SOPs, and the US PRC Operations Manual.

This is an operational leadership role rather than a meeting-administration role. The manager exercises judgment, leads cross-functional operating rhythms, challenges avoidable defects and delays, and turns portfolio signals into clear actions, owners, dates, escalations, and measurable improvements. The position serves as a primary coordination point for assigned portfolios and maintains accurate, audit-ready records and effective operational follow-through.

The role makes day-to-day coordination, sequencing, and escalation recommendations within approved PRC governance and portfolio priorities. It owns operational follow-through and evidence, while specialist medical, legal, regulatory, compliance, commercial, and contractual decisions remain with authorized functional owners. Unresolved risks, conflicting priorities, recurring quality issues, and material capacity gaps are escalated with supporting facts and a recommended path forward.

Requirements

• Bachelor's degree or equivalent relevant experience.
• Experience in promotional review, MLR/PRC operations, regulated content operations, marketing operations, or a comparable cross-functional environment.
• Demonstrated ability to manage complex portfolios, facilitate senior cross-functional stakeholders, and deliver through ambiguity.
• Working knowledge of promotional material workflows, submission readiness, lifecycle controls, records discipline, and regulated operating procedures.
• Strong analytical judgment, including the ability to interpret operational metrics, identify root causes, and convert insights into action.
• Excellent facilitation, written communication, stakeholder management, prioritization, and problem-solving skills.

Nice To Haves

• Experience with Veeva Vault PromoMats or a comparable review and approval system.
• Demonstrated launch or high-volume/campaign readiness experience; strongly preferred.
• Experience in pharmaceutical, biotech, medical, or other regulated promotional review environments.
• Experience supporting launch materials, expedited reviews, lifecycle management, SOPs, training, or process improvement initiatives.
• Experience working with agencies of record, vendors, and cross-functional review teams.

Responsibilities

• Own an integrated operating plan for assigned portfolios, covering launches, campaigns, reapprovals, expirations, and business-as-usual demand, including priorities, dependencies, owners, and dates.
• Identify emerging risks using demand, aging, quality, capacity, and workflow signals; recommend sequencing and escalate decisions when priorities compete.
• Prepare and facilitate planning and prioritization forums that translate forecasts and business priorities into executable review plans and documented commitments.
• Partner with Commercial, Medical, Regulatory, Legal, Compliance, Business Operations, agencies, vendors, and PRO leaders to align expectations and maintain decision continuity.
• Coordinate the full PRC operating cycle, including intake, readiness, routing, review cycles, meetings, decision and action documentation, final-upload verification, approved-release handoffs, reapproval, expiration alerts, and withdrawal follow-up.
• Ensure materials use the correct workflow, are review-ready, and meet applicable requirements, policies, SOPs, and operating standards.
• Maintain accurate agendas, annotations, status communications, decisions, actions, and records, and follow up through documented closure.
• Initiate and support approved escalation pathways, including ERC escalation when applicable, and document final decisions and required follow-through.
• Apply approved intake and readiness checklists to identify missing references, metadata, annotations, supporting information, and other submission defects before review.
• Document rejection, rework, and defect reasons; distinguish coordinator checks from specialist or reviewer judgment and route questions to the appropriate owner.
• Analyze monthly and in-cycle signals for repeat defects and material trends, while acting promptly on urgent risks.
• Lead documented interventions with Project Owners and agencies, establishing corrective actions, accountable owners, due dates, and effectiveness checks.
• Monitor improvement across subsequent cycles, escalate overdue or recurring issues, and contribute to Submission Excellence training, job aids, and operating standards.
• Partner with launch leads and business stakeholders to establish review forecasts, priority order, reviewer commitments, meeting cadence, dependencies, and contingency coverage for launch-critical materials.
• Anticipate volume surges and timing conflicts, surface capacity constraints early, and recommend practical mitigation plans.
• Maintain launch execution while protecting business-as-usual continuity and keeping risks, decisions, and recovery actions visible.
• Monitor volume, cycle time, aging, review readiness, quality, rework, and recurring defects, and translate findings into targeted actions.
• Intervene on aging materials at defined checkpoints by documenting blockers, next actions, owners, and resolution dates, and escalate material risks before timelines are exceeded.
• Identify and lead process, system, meeting, and operating-model improvements in partnership with PRO Process, Systems, Lifecycle, and Analytics colleagues.
• Support root-cause analysis, CAPA and deviation evidence collection, corrective-action tracking, and effectiveness checks when required.
• Communicate priorities, accountabilities, risks, and decisions clearly and promptly as the primary coordination point for assigned portfolios.
• Hold Project Owners, agencies, and vendors to approved readiness, workflow, quality, and follow-through expectations while maintaining constructive relationships.
• Support stakeholder onboarding and training on PRC processes, policies, SOPs, systems, and role responsibilities.
• Coordinate service providers and backup resources to maintain coverage and continuity, and flag scope, capacity, or service-standard concerns to PRO leadership.
• Maintain accurate records, metadata, ownership, distribution lists, rosters, calendars, templates, and portfolio documentation in approved systems and repositories.
• Support system enhancements, user acceptance testing, adoption, and change communications relevant to coordinator workflows.
• Protect audit traceability and ensure operating documents, decisions, and handoffs remain accessible, current, and sustainable during transitions.
• Model critical thinking, responsiveness, escalation discipline, independent operation, and sound judgment with minimal oversight.
• Provide backup coverage, share portfolio knowledge, and support standardized coordinator practices across the PRO organization.
• Coach newer coordinators and contribute practical scenarios, playbooks, and lessons learned to coordinator qualification and continuous learning.

Benefits

• Eligibility for short-term incentive bonuses.
• Equity-based awards for salaried roles.
• Qualified retirement programs.
• Paid time off, including vacation, holidays, and leaves.
• Health coverage.
• Dental coverage.
• Vision coverage.

What This Job Offers

• Job Type: Full-time
• Career Level: Manager