Manager, Clinical Supply Chain

Centessa Pharmaceuticals • Boston, MA

1d • Remote

About The Position

Centessa Pharmaceuticals is seeking a Manager, Clinical Supply Chain to support end-to-end planning, execution, and maintenance of uninterrupted clinical supply — including investigational product (IP), comparators, and ancillary materials — across assigned clinical programs. This role ensures compliance with GxP requirements, study timelines, and budgets while partnering cross-functionally with Clinical Operations, CMC, Quality, Regulatory, Finance, and external vendors. Reporting to the Senior Director, Clinical Supply Chain, the individual will build strong relationships with internal teams and third-party suppliers to align objectives and support successful trial execution, with particular attention to clinical forecasts, inventory systems, and IRT tools.

Requirements

• Bachelor's degree in engineering or science required.
• 3–5 years of biotech/pharma industry experience in clinical supply chain, including international experience, required.
• Working knowledge of clinical supply chain processes and GMP/GDP requirements.
• Experience coordinating cross-functional project teams and external vendors.
• Strong organizational, analytical, decision-making, and interpersonal skills, with excellent attention to detail.
• Ability to work independently in a fast-paced, dynamic environment.
• Demonstrated ability to coordinate CDMO activities supporting clinical development of pharmaceutical products.
• Ability to thrive in a small-company culture and contribute to creating and implementing processes.

Responsibilities

• Contribute to the development and execution of clinical supply strategies for early- to mid-phase clinical trials (Phase 1–3 as applicable).
• Manage clinical supply plans, demand forecasts, and inventory strategies — including tracking through Interactive Response Technology (IRT) systems — in alignment with protocol requirements and enrollment projections.
• Support packaging, labeling, distribution, and resupply activities for investigational products and comparators.
• Ensure on-time delivery of clinical supplies to depots and clinical sites globally.
• Partner with Quality, Clinical, CMC, and external CDMOs to develop, review, and approve clinical labels, and support CDMO packaging/labeling schedules to ensure supply availability.
• Interact regularly with third-party providers to manage the logistics and licenses required to ship materials from manufacturing to bulk storage facilities, courier depots, and investigator sites.
• Collaborate with CMC and QA to facilitate the document transfer required for IP/QP release by CDMOs.
• Monitor shelf-life and expiry dating, and coordinate retest/extension activities with the analytical team to ensure continuous supply.
• Manage the investigation, reporting, and communication of outcomes from temperature excursions and product complaints.
• Support product recovery activities pending investigation of IP from investigator sites, as needed.
• Communicate effectively across functional areas, applying a solid working knowledge of clinical supply chain processes.
• Author Pharmacy Manuals for clinical studies, as needed.
• Represent Supply Chain in Clinical and CMC Sub-Team meetings.

Benefits

• 401(k) plan
• company-sponsored medical, dental, vision, and life insurance
• generous paid time off
• health and wellness program

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level