Lead Researcher in Dr. Kriwacki's Lab

St. Jude Children's Research Hospital•Memphis, TN

22h•Onsite

About The Position

This is an opportunity for a Lead Researcher to join the Kriwacki lab to contribute to cutting-edge, NCI-funded research focused on fusion oncoproteins. As part of the lab and broader program team, you will support the development of key molecular reagents and experimental systems. At St. Jude Children’s Research Hospital, the brightest scientific minds face the fewest barriers, with world-class facilities, state-of-the-art technologies, extraordinary support, and a collaborative, bench-to-bedside environment. In this role, you’ll work at the intersection of molecular cloning, cell biology, and advanced imaging, helping to generate and characterize molecular tools used to study fusion oncoprotein function and biology. This is a highly collaborative environment where your contributions will directly impact innovative research programs and translational efforts. If you’re excited by hands-on science, eager to build new technical expertise, and motivated to contribute to meaningful advances in cancer biology, this is a unique opportunity to grow and have real impact.

Requirements

Bachelor’s degree in a relevant scientific area is required
5+ years of research experience is required with a Bachelor's degree.
3+ years of experience is required with a Master’s degree.
No prior experience required with a PhD.
Strong background in molecular biology, with emphasis on DNA cloning and construct design.
Hands-on experience with recombinant DNA techniques (e.g., plasmid construction, mutagenesis, viral vectors, analysis of DNA sequencing data).
Experience with confocal fluorescence microscopy and image analysis tools.
Proficiency in mammalian cell culture and transfection/transduction methods.
Ability to manage multiple projects and meet milestones and associated deadlines in a fast-paced environment.
Excellent communication, record-keeping, organization, and leadership skills.

Nice To Haves

Familiarity with studying protein-protein interactions or oncogenic fusion proteins is a plus.

Responsibilities

Design and execute molecular cloning strategies for generation of fusion oncoprotein constructs and engineered cell lines.
Develop, optimize, and troubleshoot assays to study fusion oncoprotein expression, localization, and function.
Perform and refine advanced microscopy techniques to investigate protein localization, dynamics and interactions, and cellular phenotypes.
Analyze and interpret experimental data; present findings at lab and program meetings and participate in pan-program discussions.
Collaborate closely with investigators to drive project design, execution, and troubleshooting.