Lead Clinical Lab Scientist (3rd Shift, Tues-Sat)
About The Position
Personalis is transforming cancer management through personalized testing, including assays designed to detect minimal residual disease and recurrence, support targeted therapy selection, and advance biomarker strategies. Based in Fremont, California, the company combines tumor-and-normal profiling with proprietary algorithms to provide insights as cancer evolves. The Lead Clinical Lab Scientist performs and reports clinical laboratory tests that assist physicians in diagnosing and treating patients. The role includes supporting team supervision and ensuring that procedures are followed for specimen handling, next-generation sequencing processes, test analysis, and patient-record maintenance. The lab emphasizes a positive, team-based environment and offers hands-on work across benches such as extractions, library preparation, and sequencing, in coordination with lab assistants on pre- and post-analytical tasks. This is a Tuesday–Saturday, 10:00 p.m.–6:30 a.m. shift. Training hours may differ from the regular schedule, and the PM and third shifts are eligible for an additional shift premium. The hiring range is $66.00–$82.00 per hour, plus applicable shift differential. Full-time regular positions also include an annual performance-based bonus or sales incentive plan and long-term incentive units (equity), in addition to benefits dependent on level and position.
Requirements
- Bachelor's degree, preferably in sciences or a related discipline.
- Valid California Clinical Laboratory Scientist (CLS) or Clinical Genetic Molecular Biologist Scientist (CGMBS) license.
- At least two years of CLS experience in a clinical laboratory environment.
- Demonstrated leadership capabilities.
Nice To Haves
- Four or more years of total work experience in a laboratory.
- Experience with manual or automated library preparation.
- Experience with manual or automated target enrichment.
- Experience with automated liquid handlers.
- Experience with Google Suite and Microsoft Excel.
Responsibilities
- Perform and report clinical laboratory testing on patient samples to aid physicians in diagnosis and treatment, including extractions, library preparation, and enrichments.
- Handle and process patient specimens according to laboratory procedures, ensuring accurate and timely record-keeping and reporting of results.
- Complete LIMS data entry and review signoffs.
- Select, implement, and evaluate quality control materials for statistical process control of laboratory assays.
- Troubleshoot assays and equipment when quality control materials do not perform as expected.
- Document corrective actions when test systems deviate from established performance specifications.
- Coordinate with Facilities to address building or facilities issues during the assigned shift and minimize disruption to processing.
- Work with OPS managers to report incidents and non-conformances to the Quality team.
- Assist with audits by regulatory bodies such as CAP and by external customers.
- Participate in activities supporting laboratory licensure, including quality management and on-site inspections.
- Maintain current knowledge of laboratory methods and how physicians use the resulting information through continuing education.
- Identify and correct problems that may negatively affect test performance or result reporting; notify a supervisor, clinical consultant, or director when a problem cannot be corrected immediately.
- Train other CLS and laboratory personnel on laboratory methods.
- Monitor the activities of non-licensed staff.
- As needed, oversee or supervise laboratory activities in the absence of an onsite manager.
- Guide team members in troubleshooting and deviation investigations.
- Assist in assay development activities.
- Apply analytical skills, independent critical thinking, and technical and functional knowledge to help the team meet its goals.
- Work independently to identify and resolve complex, open-ended problems.
Benefits
- Annual performance-based bonus or sales incentive plan for full-time regular positions.
- Long-term incentive units (equity) for full-time regular positions.
- Medical benefits.
- Dental insurance.
- Vision insurance.
- 401(k) match.
- Employee stock purchase plan (ESPP).
- Tuition reimbursement.
- Sick and vacation time.
- Commuter benefits.
- EV charging stations.
- Onsite gym.
- Wellness benefits.
- Applicable shift differential for PM and third shifts.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
