Lab Assistant Pediatrics

UCSF•San Francisco, CA

22h

About The Position

This position exists to support the research program of the Cromer Lab, which focuses on genome engineering and synthetic biology approaches to understand and control human hematopoietic stem and progenitor cell (HSPC) biology. The lab develops and applies CRISPR-based functional genomics tools, including pooled screening approaches, to identify genetic regulators of erythropoiesis and to enable scalable production and engineering of red blood cells for therapeutic applications. The incumbent will contribute to experimental workflows involving primary human HSPC culture, genome editing, and high-throughput CRISPR screening. This includes supporting lentiviral library production, transduction of primary cells, and downstream phenotypic and molecular analyses. The position plays a key role in advancing efforts to develop next-generation cell therapies through precise and scalable genome engineering. The Cromer Lab is part of the UCSF research community and offers a highly collaborative and interdisciplinary environment spanning stem cell biology, genome engineering, and translational science. This position provides an excellent opportunity for individuals seeking hands-on experience with cutting-edge functional genomics technologies in primary human cells, with prior lab members advancing to graduate programs, medical training, and careers in biotechnology.

Requirements

Experience with primary human HSPC culture
Experience with genome editing
Experience with high-throughput CRISPR screening
Experience supporting lentiviral library production
Experience supporting transduction of primary cells
Experience supporting downstream phenotypic and molecular analyses

Responsibilities

Contribute to experimental workflows involving primary human HSPC culture, genome editing, and high-throughput CRISPR screening.
Support lentiviral library production.
Support transduction of primary cells.
Support downstream phenotypic and molecular analyses.