Lab Assistant I (Part-Time Limited)

University of California, IrvineIrvine, CA
Onsite

About The Position

In the La Spada laboratory, we apply the tools of molecular genetics, neuroscience, and functional genomics to understand the mechanisms of neurodegenerative disease. The repertoire of diseases being actively investigated in the lab include Spinal and Bulbar Muscular Atrophy, Spinocerebellar Ataxia Types 2 and 7, Amyotrophic Lateral Sclerosis, Alzheimer's Disease, Parkinson's Disease, and Huntington's Disease. A part-time (20 hrs/wk) research intern is needed to assist on research projects at a UCI lab (La Spada, located in ISEB). This is not a work-study position. The intern will have a 1000 working hours maximum. The candidate must be able to work with flexibility depending on the animal experiments and occasional weekend work. The overall goal of the project is to investigate the role of microRNAs in spinocerebellar ataxia type 7 (SCA7) using novel mouse models and to evaluate therapeutic potential for neurodegenerative disease.

Requirements

  • Mouse handling
  • Mouse perfusion and dissection (brain, cerebellum)
  • Cryosectioning
  • RNA extraction and qPCR
  • Mouse handling and perfusions/dissections
  • RNA extraction and molecular biology techniques
  • Must be able to provide proof of work authorization

Nice To Haves

  • Immunofluorescence staining
  • Image analysis (ImageJ, NIS-Elements)

Responsibilities

  • Rodent handling
  • Perfusion
  • Dissections
  • Tissue cryosectioning
  • RNA extraction and analysis
  • Molecular biology (protein and/or RNA analysis)
  • Immunofluorescence staining
  • Microscopy
  • Computational image analysis (ImageJ, NIS-Elements)
  • Data analysis/presentation

Benefits

  • Medical insurance
  • Sick and vacation time
  • Retirement savings plans
  • Access to a number of discounts and perks
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