Human Resources Business Partner Senior Director, Data Technology & Engineering

Vertex Pharmaceuticals • Boston, MA

47d • Hybrid

About The Position

We are seeking a strategic, influential Senior Director, HR Business Partner to lead the people strategy for Vertex’s Data, Technology & AI (DTE) organization. This role partners closely with the Chief Digital & Information Officer (CDIO) and leadership team to translate business and technology priorities into an integrated talent and organizational agenda. The position plays a critical role in enabling execution of the Data/Technology/AI roadmap through leadership capability, operating model evolution, and enterprise talent strategy.

Requirements

• Bachelor’s degree required; advanced degree preferred
• 12+ years of progressive HR experience (or equivalent combination of education and experience), including significant partnership with senior leaders in complex, technology-enabled organizations
• Demonstrated experience supporting Data, Technology, Engineering, Product, AI/Analytics, or similarly technical organizations
• Proven success designing and implementing enterprise-level HR strategies and transformation initiatives
• Deep expertise in organizational effectiveness, change leadership, and organization design
• Strong understanding of Data/Technology/AI operating models and workforce implications of AI-driven transformation
• Ability to leverage data, analytics, and AI to inform decisions and improve outcomes
• Exceptional business acumen with the ability to connect talent strategy to business performance (speed, quality, risk)
• Strong executive presence and influencing skills, with the ability to coach leaders through ambiguity and change
• Agile, forward-thinking mindset with the ability to synthesize complex information into actionable strategies
• Collaborative leadership style with high emotional intelligence, integrity, and resilience
• Ability to operate effectively in a fast-paced, complex, and evolving environment
• Proven ability to lead through influence in a senior individual contributor capacity

Responsibilities

• Serve as the primary HR partner to the CDIO and DTE leadership team, translating strategy into prioritized people and organizational initiatives and influencing executive decisions with data-driven insights.
• Lead large-scale change initiatives to embed and evolve the Data/Technology/AI operating model, ensuring effective adoption of new governance, decision rights, and ways of working.
• Act as the architect for organizational design, optimizing structures, spans/layers, and operating mechanisms to improve speed, clarity, and accountability.
• Define and drive enterprise-wide talent strategies for DTE capabilities, including role architecture, skill frameworks, development pathways, and succession planning.
• Develop strategies to attract, develop, and retain high-impact technical and leadership talent, leveraging build/buy/borrow approaches, internal mobility, and reskilling initiatives.
• Coach senior leaders and leadership teams to strengthen performance, decision quality, and alignment, while leading robust talent reviews and succession processes.
• Champion a culture of innovation, collaboration, and continuous learning, reinforcing organizational health, inclusion, and sustainable high performance.
• Leverage analytics and AI to generate actionable talent insights, measure impact of HR strategies, and enhance decision-making, productivity, and outcomes.

Benefits

• medical, dental and vision benefits
• generous paid time off (including a week-long company shutdown in the Summer and the Winter)
• educational assistance programs including student loan repayment
• a generous commuting subsidy
• matching charitable donations
• 401(k)

What This Job Offers

• Job Type: Full-time
• Career Level: Senior