Empress: Genomics Co-Op
About The Position
Empress is pioneering mechanistic intelligence for drug discovery — helping R&D teams understand what their molecules are doing, what is driving activity, what liabilities may emerge, and which candidates are best positioned to advance. By integrating multi-omics, chemoproteomics, proteomics, transcriptomics, computational inference, knowledge graphs, and CRISPR-based functional validation, Empress turns biological complexity into clearer development decisions. Our platform gives discovery teams access to capabilities that would otherwise require years, specialized infrastructure, and rare cross-functional expertise to build internally. Empress is a privately held biotech conceived by Flagship Pioneering, which brings the courage, long-term vision, and resources needed to realize unreasonable results. The Role We're looking for a Co-op to join our Genomics team and contribute to the development of Empress's Integromyx and Perturb-seq platforms. This is a real opportunity to do meaningful bench work. You'll design and execute molecular cloning workflows, maintain mammalian cell cultures, and apply qRT-PCR for transcriptional profiling, with the potential to get hands-on with CRISPR-Cas9 cell line engineering. You'll work as part of a cross-functional team where your contributions matter from day one. We're looking for someone who is curious, detail-oriented, and excited to develop their skills in a fast-moving environment.
Requirements
- Currently enrolled in a B.S. or M.S. program in Molecular Biology, Genetics, Biochemistry, or a related field
- Coursework or hands-on laboratory experience in molecular biology, nucleic acid manipulation, or synthetic biology
Nice To Haves
- NGS sample preparation experience, including Illumina and/or Oxford Nanopore platforms
- Familiarity with R, Python, or strong interest in learning informatics tools
- Interest in lab automation instrumentation
- Prior experience with mammalian cell culture
Responsibilities
- Design, generate, and validate plasmids using Golden Gate cloning and other synthetic biology methodologies
- Maintain mammalian cell cultures; perform transductions, transfections, and routine cell culture husbandry
- Produce lentiviral vectors to support cell line engineering workflows
- Apply qPCR/ qRT-PCR and other molecular biology techniques to support research objectives
- Contribute to CRISPR-Cas9-based mammalian cell line engineering experiments
- Present findings in team and cross-functional meetings; maintain meticulous electronic lab notebook records
Benefits
- Retirement benefits may be available after completing a set number of hours.
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What This Job Offers
Career Level
Entry Level
Education Level
Associate degree
